Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression. Off-label indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label].
Marketing Status Prescription
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 69097-823; 42806-020; 70518-0561; 43063-385; 43353-112; 70518-2228; 65162-054; 67046-102; 71610-092; 0456-4020; 50090-5170; 69097-824; 68788-7899; 70518-2617; 43063-063; 70934-539; 65162-052; 54458-980; 69097-822; 70518-2553; 0054-0062; 52427-691; 60429-174; 67046-106; 76282-629; 61919-390; 76282-628; 50090-5172; 54458-889; 70518-2601; 70518-2671; 54458-981; 0378-6233; 71335-0541; 60429-173; 71610-412; 63850-3616; 65162-053; 0378-6231; 0456-4010; 42806-021; 76282-206; 68071-3034; 67046-101; 70518-0449; 60429-175; 70934-397; 43353-208; 50090-5175; 63629-6761; 0456-4040; 61919-389; 76282-208; 71610-422; 80425-0093; 76282-207; 0378-6232; 43353-091; 42806-019
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hostility19.05.01.003--Not Available
Hunger14.03.02.012; 08.01.09.0030.000083%Not Available
Hydrocele21.12.02.003; 03.03.01.0040.000333%Not Available
Hydrocephalus17.07.01.0010.000208%
Hydronephrosis20.01.05.0010.000083%Not Available
Hyperacusis17.04.03.003; 04.02.02.0010.000125%Not Available
Hyperaesthesia17.02.06.004--Not Available
Hyperammonaemia14.10.01.001; 09.01.02.0020.000208%Not Available
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.0020.000250%
Hyperhidrosis23.02.03.004; 08.01.03.0280.001708%
Hyperkalaemia14.05.03.0010.000375%
Hyperkinesia17.01.02.008--Not Available
Hyperlactacidaemia14.01.01.0060.000167%Not Available
Hyperprolactinaemia05.03.01.002--Not Available
Hyperreflexia17.02.01.0020.000500%Not Available
Hypersensitivity10.01.03.0030.001708%
Hypersomnia19.02.05.001; 17.15.01.0010.000167%
Hypertension24.08.02.001--
Hypertensive crisis24.08.01.0010.000250%Not Available
Hyperthermia12.05.01.002; 08.05.01.0010.000292%Not Available
Hyperthyroidism14.11.01.011; 05.02.02.0010.000125%
Hypertonia17.05.02.001; 15.05.04.0070.000250%Not Available
Hypertrichosis23.02.04.002--
Hypertrophic cardiomyopathy03.07.02.004; 02.04.01.0020.000043%Not Available
Hyperventilation22.02.01.006; 19.01.02.0040.000083%Not Available
Hypoaesthesia17.02.06.0230.001541%Not Available
Hypocalcaemia14.04.01.004--
Hypochromic anaemia01.03.02.004--Not Available
Hypocoagulable state01.01.02.0040.000208%Not Available
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