| Pharmaceutical Information |
| Drug Name |
Cisatracurium besylate |
| Drug ID |
BADD_D00473 |
| Description |
Cisatracurium is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action. |
| Indications and Usage |
For inpatients and outpatients as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation in the ICU. |
| Marketing Status |
Prescription |
| ATC Code |
M03AC11 |
| DrugBank ID |
DB00565
|
| KEGG ID |
D00759
|
| MeSH ID |
C101584
|
| PubChem ID |
62886
|
| TTD Drug ID |
D08ALK
|
| NDC Product Code |
0781-3153; 70710-1533; 58175-0541; 0781-3150; 40016-007; 70710-1532; 0409-3670; 70069-161; 0409-1103; 55150-284; 53183-4014; 0074-4378; 0703-2033; 71288-720; 70069-151; 63323-416; 72785-0009; 70069-141; 0409-5547; 0409-1208; 72785-0008; 0409-1098; 0074-4382; 57884-0018; 55150-286; 0703-2056; 72785-0011; 0074-4380; 43798-462; 0703-2045; 24584-1112; 0781-3152; 71288-712; 25021-668; 63323-418; 25021-669; 17404-1024; 70710-1534; 24584-1110; 25021-670; 71288-714; 0409-7083; 24584-1111; 71288-713; 63323-417 |
| Synonyms |
cisatracurium | cisatracurium besylate | cisatracurium besilate | Nimbex | 51W89 |
|
| Chemical Information |
| Molecular Formula |
C65H82N2O18S2 |
| CAS Registry Number |
96946-42-8 |
| SMILES |
C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CC
C5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C
=C1)S(=O)(=O)[O-] |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
