Drug Name |
Cimetidine hydrochloride |
Drug ID |
BADD_D00468 |
Description |
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy. |
Indications and Usage |
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion. |
Marketing Status |
Prescription; OTC; Discontinued |
ATC Code |
A02BA01 |
DrugBank ID |
DB00501
|
KEGG ID |
D03503
|
MeSH ID |
D002927
|
PubChem ID |
50963
|
TTD Drug ID |
D02DPA
|
NDC Product Code |
0121-0649; 50383-966; 0121-1298; 49964-0019 |
Synonyms |
Cimetidine | N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine | Biomet | Biomet400 | Cimetidine Hydrochloride | Hydrochloride, Cimetidine | Cimetidine HCl | HCl, Cimetidine | Histodil | SK&F-92334 | SK&F 92334 | SK&F92334 | SKF-92334 | SKF 92334 | SKF92334 | Tagamet | Altramet | Eureceptor |