Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ciclesonide
Drug ID BADD_D00460
Description Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Indications and Usage For the treatment of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents 12 years of age and older.
Marketing Status Prescription
ATC Code R01AD13; R03BA08
DrugBank ID DB01410
KEGG ID D01703
MeSH ID C120481
PubChem ID 6918155
TTD Drug ID D0K7HU
NDC Product Code 70515-701; 64918-1900; 53104-7633; 70515-712; 24002-0016; 70515-711; 70515-737; 64918-1112
Synonyms ciclesonide | (R)-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate | Alvesco | Omnaris
Chemical Information
Molecular Formula C32H44O7
CAS Registry Number 126544-47-6
SMILES CC(C)C(=O)OCC(=O)C12C(CC3C1(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)OC(O2)C6CCCCC6
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.005--Not Available
Malaise08.01.01.0030.003141%
Malignant melanoma16.03.01.001; 23.08.01.0010.001570%Not Available
Multiple fractures15.08.02.005; 12.04.02.009--Not Available
Myalgia15.05.02.0010.001570%
Nasal congestion22.04.04.001--
Nasal dryness22.04.03.002--Not Available
Nasal septum disorder22.04.03.015--Not Available
Nasal septum perforation22.04.03.003--Not Available
Nasal ulcer22.04.03.011--Not Available
Nasopharyngitis22.07.03.002; 11.01.13.0020.001570%Not Available
Nausea07.01.07.0010.003141%
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.001570%
Oral candidiasis07.05.07.001; 11.03.03.004--Not Available
Osteoporosis15.02.03.002; 14.04.04.002--
Pain in extremity15.03.04.010--
Palpitations02.01.02.003--
Pharyngeal oedema23.04.01.016; 22.04.05.003; 10.01.05.016--Not Available
Pharyngitis11.01.13.003; 07.05.07.004; 22.07.03.004--
Pharyngitis streptococcal22.07.04.001; 11.02.06.002--Not Available
Pleural effusion22.05.02.0020.001570%
Pneumonia22.07.01.003; 11.01.09.0030.003926%Not Available
Pruritus23.03.12.0010.003926%
Pulmonary embolism24.01.06.001; 22.06.02.0010.000410%Not Available
Pulmonary fibrosis22.01.02.0060.000410%
Pyrexia08.05.02.0030.002356%
Rash23.03.13.0010.002356%Not Available
Respiratory failure22.02.06.002; 14.01.04.0030.000410%
Rhinitis22.07.03.006; 11.01.13.0040.001570%
Rhinitis allergic22.04.04.003; 10.01.04.003--
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