| Pharmaceutical Information |
| Drug Name |
Choline fenofibrate |
| Drug ID |
BADD_D00455 |
| Description |
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration.[A32038,A193362] |
| Indications and Usage |
For use as an adjunctive therapy to diet to: (a) reduce triglyceride levels in adult patients with severe hypertriglyceridemia, and (b) reduce elevated total cholesterol, low-density-lipoprotein (LDL-C), triglycerides, and apolipoprotein B, and to increase high-density-lipoprotein (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). [FDA Label] |
| Marketing Status |
Prescription |
| ATC Code |
C10AB11 |
| DrugBank ID |
DB13873
|
| KEGG ID |
D08890
|
| MeSH ID |
Not Available
|
| PubChem ID |
11350701
|
| TTD Drug ID |
D01HKL
|
| NDC Product Code |
17337-0013; 17337-0042; 17180-0201; 17337-0412; 66039-874; 68294-0003; 66064-1007 |
| Synonyms |
Not Available |
|
| Chemical Information |
| Molecular Formula |
C22H28ClNO5 |
| CAS Registry Number |
856676-23-8 |
| SMILES |
CC(C)(C(=O)[O-])OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl.C[N+](C)(C)CCO |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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