Drug Name |
Choline fenofibrate |
Drug ID |
BADD_D00455 |
Description |
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration.[A32038,A193362] |
Indications and Usage |
For use as an adjunctive therapy to diet to: (a) reduce triglyceride levels in adult patients with severe hypertriglyceridemia, and (b) reduce elevated total cholesterol, low-density-lipoprotein (LDL-C), triglycerides, and apolipoprotein B, and to increase high-density-lipoprotein (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). [FDA Label] |
Marketing Status |
Prescription |
ATC Code |
C10AB11 |
DrugBank ID |
DB13873
|
KEGG ID |
D08890
|
MeSH ID |
Not Available
|
PubChem ID |
11350701
|
TTD Drug ID |
D01HKL
|
NDC Product Code |
17337-0013; 17337-0042; 17180-0201; 17337-0412; 66039-874; 68294-0003; 66064-1007 |
Synonyms |
Not Available |