Drug Name |
Chlorpromazine hydrochloride |
Drug ID |
BADD_D00446 |
Description |
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup. |
Indications and Usage |
For the treatment of schizophrenia; to control nausea and vomiting; for relief of restlessness and apprehension before surgery; for acute intermittent porphyria; as an adjunct in the treatment of tetanus; to control the manifestations of the manic type of manic-depressive illness; for relief of intractable hiccups; for the treatment of severe behavioral problems in children (1 to 12 years of age) marked by combativeness and/or explosive hyperexcitable behavior (out of proportion to immediate provocations), and in the short-term treatment of hyperactive children who show excessive motor activity with accompanying conduct disorders consisting of some or all of the following symptoms: impulsivity, difficulty sustaining attention, aggressivity, mood lability, and poor frustration tolerance. |
Marketing Status |
Discontinued; Prescription |
ATC Code |
N05AA01 |
DrugBank ID |
DB00477
|
KEGG ID |
D00789
|
MeSH ID |
D002746
|
PubChem ID |
6240
|
TTD Drug ID |
D01ZII
|
NDC Product Code |
60687-441; 69238-1054; 0832-6021; 70710-1129; 60687-430; 0527-2961; 69238-1056; 70518-3321; 70771-1506; 0832-0302; 0832-0301; 0904-7129; 0904-6894; 70518-1608; 70771-1507; 60687-452; 42413-0137; 68462-863; 0641-1397; 0527-2965; 70771-1510; 69238-1058; 70771-1509; 60687-419; 70710-1131; 0832-6020; 0832-0304; 55150-318; 90096-135; 0404-9836; 0904-6896; 52584-397; 72205-106; 90096-134; 68462-864; 72205-105; 51407-437; 24338-410; 70518-3348; 58793-013; 70518-0016; 82298-901; 50396-7515; 67763-115; 69238-1060; 73435-001; 50268-163; 0641-1398; 68462-865; 90096-131; 0904-6892; 0527-2964; 64950-241; 0904-7132; 0832-0303; 70771-1508; 90096-132; 90096-133; 69238-1062; 55150-319; 16714-047; 0781-5917; 70966-0017; 50090-2791; 68462-862; 70518-3034; 70710-1133; 24338-403; 70710-1132; 50090-2865; 16714-049; 0527-2962; 0781-5914; 71554-002; 51407-436; 50268-166; 70710-1130; 68462-861; 0904-7131; 70518-3086; 16714-050; 53808-1104; 72166-004; 70518-3280; 0781-5913; 60687-463; 50268-162; 72205-107; 0832-6019; 50268-164; 62991-1425; 0904-7133; 16714-048; 50268-165; 0832-6017; 51407-438; 38779-0423; 72205-104; 64950-240; 71666-006; 0904-6895; 0832-6018; 51552-0139; 51407-435; 51407-434; 16714-051; 0832-0300; 0527-2963; 0904-7130 |
Synonyms |
Chlorpromazine | Thorazine | Aminazine | Largactil | Chlordelazine | Chlorpromazine Hydrochloride | Hydrochloride, Chlorpromazine | Contomin | Fenactil | Propaphenin | Chlorazine |