Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status approved
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9569; 0143-9976; 0143-9568; 0143-9977; 0143-9979
UNII O1R9FJ93ED
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pallor24.03.04.001; 23.03.03.031; 08.01.03.0320.000572%Not Available
Palpitations02.11.04.0120.000773%
Pancytopenia01.03.03.003--Not Available
Papule23.03.03.0380.000143%Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Paralysis17.01.04.0040.000143%Not Available
Paresis17.01.04.0080.000143%Not Available
Parosmia22.04.03.007; 17.04.04.0020.000386%Not Available
Periorbital oedema06.08.03.017; 23.04.01.002; 10.01.05.0100.000358%
Pharyngeal oedema23.04.01.016; 22.04.05.003; 10.01.05.0160.000286%Not Available
Photopsia17.17.01.006; 06.02.06.0040.000143%
Photosensitivity reaction23.03.09.0030.000315%
Pleural effusion22.05.02.002--
Premature baby18.04.02.0010.000358%Not Available
Premature delivery18.07.01.0060.000215%
Premature rupture of membranes18.07.01.0030.000143%Not Available
Proteinuria20.02.01.0110.000143%
Prothrombin level increased13.01.02.011--Not Available
Prothrombin time prolonged13.01.02.012--Not Available
Pruritus23.03.12.0010.006524%
Pseudomembranous colitis07.19.01.003; 11.02.02.002--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.0030.000215%
Pustular psoriasis10.02.01.102; 23.03.14.0060.000215%Not Available
Pyrexia08.05.02.0030.003505%
Rales22.12.01.0110.000215%Not Available
Rash23.03.13.0010.007182%Not Available
Rash erythematous23.03.13.0290.000143%Not Available
Rash macular23.03.13.0030.000458%Not Available
Rash maculo-papular23.03.13.0040.001316%
Rash morbilliform23.03.13.0050.000315%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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