Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status Prescription
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9977; 0143-9569; 0143-9979; 0143-9976; 0143-9568
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eyelid oedema23.04.01.003; 10.01.05.001; 06.04.04.0040.001277%Not Available
Face oedema08.01.07.003; 23.04.01.004; 10.01.05.0020.003193%
Fatigue08.01.01.002--
Feeling hot08.01.09.0090.000639%Not Available
Flatulence07.01.04.0020.001277%
Flushing23.06.05.003; 08.01.03.025; 24.03.01.0020.003512%
Frequent bowel movements07.02.04.0020.000639%Not Available
Gait disturbance08.01.02.002; 17.02.05.016--
Gastroenteritis11.01.07.004; 07.19.03.0010.000639%Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal infection11.01.07.012; 07.19.02.005--Not Available
Gastrointestinal pain07.01.05.005--
Glaucoma06.03.01.0020.000639%
Haematocrit decreased13.01.05.001--Not Available
Haematoma24.07.01.0010.000639%
Haemoglobin13.01.05.018--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Heart rate decreased13.14.04.0010.000958%Not Available
Heart rate increased13.14.04.002--Not Available
Hepatic failure09.01.03.0020.000167%
Hepatic function abnormal09.01.02.001--Not Available
Hepatitis09.01.07.0040.000639%Not Available
Hepatosplenomegaly01.09.03.001; 09.01.05.0020.000639%Not Available
Hyperhidrosis23.02.03.004; 08.01.03.0280.004151%
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.0030.015007%
Hypersensitivity vasculitis24.05.02.012; 23.06.02.005; 10.02.02.017; 01.01.04.0080.000333%Not Available
Hypoaesthesia17.02.06.023--Not Available
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