Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ceftaroline fosamil
Drug ID BADD_D00398
Description Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
Indications and Usage Ceftaroline fosamil is indicated for the treatment of patients with the following infections caused by susceptible isolates of the designated microorganisms.
Marketing Status Prescription
ATC Code J01DI02
DrugBank ID DB06590
KEGG ID D08884
MeSH ID C515501
PubChem ID 9852981
TTD Drug ID Not Available
NDC Product Code 52946-0918; 0456-0600; 0456-0400
Synonyms ceftaroline fosamil | Teflaro | TAK-599 | TAK599 | PPI-0903 | PPI0903
Chemical Information
Molecular Formula C22H21N8O8PS4
CAS Registry Number 229016-73-3
SMILES CCON=C(C1=NSC(=N1)NP(=O)(O)O)C(=O)NC2C3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C= C5)C)C(=O)[O-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.0010.000319%Not Available
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.0010.000319%
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Clostridium difficile colitis07.19.01.004; 11.02.02.004--Not Available
Constipation07.02.02.001--
Coombs direct test positive13.01.01.001--Not Available
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspnoea22.02.01.004; 02.01.03.0020.000213%
Encephalitis11.01.03.008; 17.06.05.0010.000213%
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.0030.000213%
Fluid overload14.05.06.001; 02.05.04.0040.000213%Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haemolytic anaemia01.06.03.0020.000213%Not Available
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypokalaemia14.05.03.002--
Immune system disorder10.02.01.001--Not Available
The 1th Page    1 2 3    Next   Last    Total 3 Pages