| Pharmaceutical Information |
| Drug Name |
Buserelin acetate |
| Drug ID |
BADD_D00315 |
| Description |
Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). It is used in prostate cancer treatment. |
| Indications and Usage |
Buserelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. |
| Marketing Status |
Not Available |
| ATC Code |
L02AE01 |
| DrugBank ID |
DB06719
|
| KEGG ID |
D01831
|
| MeSH ID |
D002064
|
| PubChem ID |
50224
|
| TTD Drug ID |
D04GSY
|
| NDC Product Code |
71052-358 |
| Synonyms |
Buserelin | Buserelin Acetate | Acetate, Buserelin | Suprefact | Profact | Receptal | Tiloryth | Suprecur | Bigonist | HOE-766 | HOE 766 | HOE766 |
|
| Chemical Information |
| Molecular Formula |
C62H90N16O15 |
| CAS Registry Number |
68630-75-1 |
| SMILES |
CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(COC(C)(C)C)NC(=O)C(CC2=C
C=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(
=O)N6.CC(=O)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
