Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bumetanide
Drug ID BADD_D00307
Description Bumetanide is a sulfamyl diuretic.
Indications and Usage For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
Marketing Status Prescription; Discontinued
ATC Code C03CA02
DrugBank ID DB00887
KEGG ID D00247
MeSH ID D002034
PubChem ID 2471
TTD Drug ID D0R7HO
NDC Product Code 0185-0129; 17337-0011; 51662-1449; 50268-130; 30698-631; 50090-5123; 68071-4330; 60687-384; 50090-5663; 30698-630; 14539-701; 0641-6008; 69238-1489; 42799-120; 68071-3128; 68382-526; 50090-5064; 50268-131; 16714-832; 14539-700; 68382-527; 70518-2678; 14501-0036; 0904-7016; 60468-001; 72572-041; 0832-0542; 70860-405; 70771-1026; 0185-0130; 50090-5666; 43353-288; 0641-6007; 68382-525; 50268-132; 0409-1412; 14539-702; 50090-5124; 0832-0541; 42799-119; 0832-0540; 50090-5065; 57755-0004; 63629-7440; 55154-4733; 0615-8394; 70771-1024; 63190-0430; 16714-831; 0641-6161; 71335-1692; 60687-535; 71335-1201; 50090-5068; 63190-0370; 0615-8361; 0615-8362; 16714-833; 0615-8393; 63629-4968; 60468-003; 42799-121; 0185-0128; 43353-292; 72572-040; 70860-406; 69238-1491; 50090-5664; 55154-4345; 70771-1025; 71335-0016; 17337-0055; 68071-4350; 60468-002; 30698-632; 55154-3572; 70518-3191; 0641-6162; 69238-1490
Synonyms Bumetanide | Bumethanide | Bumex | PF-1593 | PF 1593 | PF1593 | Drenural | Fordiuran | Miccil | Bumedyl | Burinex
Chemical Information
Molecular Formula C17H20N2O5S
CAS Registry Number 28395-03-1
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dyspnoea22.02.01.004; 02.01.03.0020.003861%
Electrocardiogram abnormal13.14.05.001--Not Available
Electrolyte imbalance14.05.01.002--Not Available
Encephalopathy17.13.02.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Fluid overload14.05.06.001; 02.05.04.0040.001931%Not Available
Fluid retention20.01.02.003; 14.05.06.0020.001931%Not Available
Gastrointestinal pain07.01.05.005--
Glycosuria20.02.01.005--
Glucose urine present13.13.02.001--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Haematocrit13.01.05.017--Not Available
Haemoglobin abnormal13.01.05.011--Not Available
Headache17.14.01.001--
Hepatocellular injury09.01.07.008--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkalaemia14.05.03.0010.001287%
Hyperuricaemia14.09.01.003--
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypochloraemia14.05.08.003--Not Available
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.0010.002574%
Hyponatraemia14.05.04.0020.004505%
Hypotension24.06.03.0020.003861%
Hypovolaemia14.05.05.0020.001287%Not Available
Leukopenia01.02.02.001--Not Available
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.001287%Not Available
Malaise08.01.01.0030.001931%
The 2th Page    First    Pre   2 3 4    Next   Last    Total 4 Pages