Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Balsalazide disodium
Drug ID BADD_D00211
Description Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine to the large intestine to act directly on ulcerative colitis. Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA.
Indications and Usage For the treatment of mildly to moderately active ulcerative colitis.
Marketing Status Prescription
ATC Code A07EC04
DrugBank ID DB01014
KEGG ID D02715
MeSH ID C038637
PubChem ID 135413496
TTD Drug ID D0A6KR
NDC Product Code 72789-149; 42291-157; 50268-102; 60505-2575; 63629-8301; 65649-101; 0054-0079; 12598-6026
Synonyms balsalazide | 5-(carboxyethylcarbamoyl-4-phenylazo)salicylic acid | BX 661A | BX661A | Colazide | balsalazine | balsalazide disodium | Colazal
Chemical Information
Molecular Formula C17H13N3Na2O6
CAS Registry Number 82101-18-6
SMILES C1=CC(=CC=C1C(=O)NCCC(=O)[O-])N=NC2=CC(=C(C=C2)[O-])C(=O)O.[Na+].[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alopecia23.02.02.001--
Alveolitis22.01.01.001--Not Available
Arthralgia15.01.02.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Fatigue08.01.01.002--
Flatulence07.01.04.002--
Headache17.14.01.001--
Influenza like illness08.01.03.010--
Insomnia19.02.01.002; 17.15.03.002--
Muscle spasms15.05.03.004--
Myalgia15.05.02.001--
Myocarditis02.04.03.001--
Nausea07.01.07.001--
Pancreatitis07.18.01.001--
Pericarditis02.06.02.001--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pleural effusion22.05.02.002--
Pneumonia11.01.09.003; 22.07.01.003--Not Available
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Renal failure20.01.03.005--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Urinary tract infection20.08.02.001; 11.01.14.004--
Vasculitis24.05.02.001; 10.02.02.006--
Vomiting07.01.07.003--
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