Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aztreonam
Drug ID BADD_D00206
Description A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Indications and Usage For the treatment of the following infections caused by susceptible gram-negative microorganisms: urinary tract infections, lower respiratory tract infections, septicemia, skin and skin-structure infections, intra-abdominal infections, and gynecologic infections.
Marketing Status Prescription; Discontinued
ATC Code J01DF01
DrugBank ID DB00355
KEGG ID D00240
MeSH ID D001398
PubChem ID 2274
TTD Drug ID D0F2XV
NDC Product Code 0003-2570; 61958-0901; 0409-0830; 63323-401; 13538-001; 13538-008; 24525-0025; 63323-402; 0003-2560; 0409-0829; 54087-160; 13538-009; 52952-001
Synonyms Aztreonam | Az-threonam | Az threonam | Azthreonam | SQ-26,776 | SQ 26,776 | SQ26,776 | Urobactam | Azactam
Chemical Information
Molecular Formula C13H17N5O8S2
CAS Registry Number 78110-38-0
SMILES CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.003--
Vulvovaginal candidiasis21.14.02.003; 11.03.03.005--Not Available
Wheezing22.03.01.009--
Acute generalised exanthematous pustulosis23.03.10.002; 12.03.01.0050.000319%Not Available
Localised oedema14.05.06.009; 02.05.04.006; 08.01.07.0110.000319%
Platelet count increased13.01.04.002--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Injection site swelling08.02.03.017; 12.07.03.018--Not Available
Transaminases increased13.03.01.0150.000213%Not Available
Haemorrhage24.07.01.002--Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.003--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Induration08.01.03.020--Not Available
Coombs test positive13.01.01.002--Not Available
Electrocardiogram change13.14.05.014--Not Available
Ill-defined disorder08.01.03.049--Not Available
Vulvovaginal mycotic infection21.14.02.004; 11.03.05.004--Not Available
Candida infection11.03.03.021--
Clostridium difficile infection11.02.02.0090.000639%Not Available
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