Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Atropine sulfate
Drug ID BADD_D00190
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D02069
MeSH ID D001285
PubChem ID 60196398
TTD Drug ID D0RG3O
NDC Product Code 51662-1509; 51662-1527; 0404-9823; 0404-9822; 13985-606; 52584-630; 0409-1630; 51552-1391; 0641-6006; 50268-118; 71872-7100; 70518-3120; 38779-2267; 71872-7037; 52584-002; 76329-3340; 51662-1339; 50090-4524; 51662-1311; 0404-9820; 52584-401; 63323-580; 50090-5924; 16729-512; 0409-4910; 50090-3138; 0409-4911; 16729-483; 52584-910; 0404-9821; 71872-7255; 0404-9824; 52584-029; 13371-387; 63827-1014; 71872-7002; 69205-736; 71872-7001; 71872-7245; 0517-1010; 0641-6251; 0404-9819; 16729-484; 76329-3339; 0409-9630; 16729-526; 43235-0004; 51662-1378; 51662-1289; 50090-3104; 52584-044; 51662-1207; 12714-031; 42385-736; 17478-215; 71684-0303; 70121-1705; 0517-0401; 62991-2842; 60505-6226; 62068-306; 52221-107; 55742-124; 76003-0157; 51662-1208; 71872-7246; 69205-031; 16729-525; 71872-7017; 0065-0303; 71872-7252; 24208-825; 51927-0156
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C34H48N2O10S
CAS Registry Number 55-48-1
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.OS(= O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Atrial fibrillationNot AvailableF1PE02Not AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemoglobin increased13.01.05.004--
Hallucination19.10.02.002--
Hallucination, auditory19.10.02.003--Not Available
Hallucination, visual19.10.02.004--Not Available
Headache17.14.01.001--
Heterophoria06.05.02.001; 17.02.05.017--Not Available
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperpyrexia08.05.02.002--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypoaesthesia eye17.02.06.019; 06.01.01.007--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypokalaemia14.05.03.002--
Hyponatraemia14.05.04.002--
Ileus paralytic07.02.05.001--Not Available
Impaired gastric emptying07.02.02.004--
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Labile blood pressure24.06.01.001--Not Available
Lacrimation increased06.08.02.004--
Laryngitis22.07.03.001; 11.01.13.001--
Laryngospasm22.04.02.002--
Left ventricular failure02.05.02.001--Not Available
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
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