Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alomide
Drug ID BADD_D00081
Description Lodoxamide is a mast-cell stabilizer for topical administration into the eye. Mast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis. These conditions often require treatment with anti-inflammatory medications such as ophthalmic NSAIDs or topical steroids which may cause systemic or toxic effects long-term. Although less effective than topical steroids at decreasing inflammation, mast-cell stabilizers offer another treatment option and exhibit minimal adverse effects. Lodoxamide is marketed under the brand name Alomide by Alcon.
Indications and Usage Indicated in the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
Marketing Status Prescription
ATC Code S01GX05
DrugBank ID DB06794
KEGG ID D04762
MeSH ID C022028
PubChem ID 44563
TTD Drug ID Not Available
NDC Product Code 58567-102
Synonyms lodoxamide tromethamine | U 42585 E | U-42,585E | Alomide
Chemical Information
Molecular Formula C15H17ClN4O9
CAS Registry Number 63610-09-3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Asthenia08.01.01.001--Not Available
Blepharitis23.03.04.012; Available
Conjunctival oedema06.04.01.001--Not Available
Corneal abrasion12.01.04.001; Available
Corneal erosion06.06.03.003--Not Available
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dry eye06.08.02.001--
Eye pain06.08.03.002--
Feeling hot08.01.09.009--Not Available
Hyperaemia24.03.02.002--Not Available
Keratopathy06.06.03.007--Not Available
Lacrimation increased06.08.02.004--
Nasal dryness22.04.03.002--Not Available
Oedema14.05.06.010; Available
Rash23.03.13.001--Not Available
Scab23.03.03.004--Not Available
Swelling08.01.03.015--Not Available
Ulcer08.03.06.001--Not Available
The 1th Page    1 2    Next   Last    Total 2 Pages