Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alitretinoin
Drug ID BADD_D00075
Description An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute).
Indications and Usage For topical treatment of cutaneous lesions in patients with AIDS-related Kaposi's sarcoma.
Marketing Status Prescription
ATC Code D11AH04; L01XF02
DrugBank ID DB00523
KEGG ID D02815
MeSH ID D000077556
PubChem ID 449171
TTD Drug ID Not Available
NDC Product Code 59212-601; 17337-0007; 17337-0008; 48943-0012
Synonyms Alitretinoin | 9cRA Compound | 9-cis-Retinoic Acid | 9 cis Retinoic Acid | BAL4079 | Panretin | Toctino
Chemical Information
Molecular Formula C20H28O2
CAS Registry Number 5300-03-8
SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tenderness08.01.08.005--Not Available
Excoriation23.03.11.003; 12.01.06.007--Not Available
Eschar23.03.03.027; 12.01.08.008--Not Available
Lymphatic disorder01.09.01.003--Not Available
Haemorrhage24.07.01.002--Not Available
Angiopathy24.03.02.007--Not Available
Bacterial infection11.02.01.005--Not Available
Inflammation08.01.05.007--Not Available
Blood disorder01.05.01.004--Not Available
Autoimmune disorder10.04.04.003--
The 2th Page    First    Pre   2    Total 2 Pages