Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Albendazole
Drug ID BADD_D00052
Description A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Indications and Usage For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Marketing Status Prescription; Discontinued
ATC Code P02CA03
DrugBank ID DB00518
KEGG ID D00134
MeSH ID D015766
PubChem ID 2082
TTD Drug ID D00KVO
NDC Product Code 73309-129; 49452-0003; 63629-1221; 43598-452; 70771-1103; 72205-051; 70710-1021; 16714-907; 42799-110; 31722-935; 69539-151; 69097-237; 72643-008; 0591-2712; 72969-104; 51927-1763; 82195-300; 52286-5500; 51407-258; 64896-693; 0115-1701; 52286-0001; 51927-0068; 60592-002; 69766-026; 53104-7736; 86055-0004; 42291-093; 78482-110
Synonyms Albendazole | Lurdex | Bilutac | Metiazol | Andazol | Albenza | Zentel | Albendoral | Albendazole Monohydrochloride | Monohydrochloride, Albendazole | Bendapar | Digezanol | Disthelm | Mediamix V Disthelm | Endoplus | Eskazole | Gascop | SK&F-62979 | SK&F 62979 | SK&F62979 | SKF-62979 | SKF 62979 | SKF62979 | Valbazen
Chemical Information
Molecular Formula C12H15N3O2S
CAS Registry Number 54965-21-8
SMILES CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Palpitations02.01.02.0030.007503%
Pancytopenia01.03.03.003--Not Available
Pruritus23.03.12.0010.037514%
Pyrexia08.05.02.0030.078779%
Rash23.03.13.0010.015006%Not Available
Rhabdomyolysis15.05.05.002--
Seizure17.12.03.0010.007503%
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.0030.007503%Not Available
Skin ulcer23.07.03.003; 24.04.03.0070.022508%
Somnolence17.02.04.006; 19.02.05.003--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.0200.015006%
Tachycardia02.03.02.0070.007503%Not Available
Testicular swelling21.13.01.0030.007503%Not Available
Thrombocytopenia01.08.01.002--Not Available
Tongue ulceration07.14.01.0030.007503%Not Available
Toxic encephalopathy17.13.01.004; 12.03.01.0270.007503%Not Available
Toxic epidermal necrolysis11.07.01.006; 10.01.01.006; 23.03.01.008; 12.03.01.0150.004893%
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.0030.011254%
Vision blurred17.17.01.010; 06.02.06.0070.015006%
Vomiting07.01.07.0030.037514%
Weight decreased13.15.01.0050.007503%
Abasia17.02.05.035; 08.01.02.0070.033762%Not Available
Lymphatic disorder01.09.01.003--Not Available
Pruritus generalised23.03.12.0030.007503%Not Available
Helicobacter infection11.02.18.0010.007503%Not Available
Hepatic enzyme increased13.03.01.019--Not Available
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