Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Abiraterone
Drug ID BADD_D00014
Description Abiraterone is a derivative of steroidal progesterone and is an innovative drug that offers clinical benefit to patients with hormone refractory prostate cancer. Abiraterone is administered as an acetate salt prodrug because it has a higher bioavailability and less susceptible to hydrolysis than abiraterone itself. FDA approved on April 28, 2011.
Indications and Usage Used in combination with prednisone for the treatment of metastatic, castration-resistant prostate cancer.
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB05812
KEGG ID Not Available
MeSH ID C089740
PubChem ID 132971
NDC Product Code 17337-0082; 30007-838; 42291-073; 60687-455; 69238-1165; 42291-024; 69238-1754; 54893-0070
Synonyms abiraterone | 17-(3-pyridyl)androsta-5,16-dien-3beta-ol | CB-7598 | CB 7598 | CB7598
Chemical Information
Molecular Formula C24H31NO
CAS Registry Number 154229-19-3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Abnormal dreams19.02.03.001; Available
Abnormal faeces07.01.03.0010.002206%Not Available
Abscess11.01.08.0010.002206%Not Available
Acne23.02.01.001--Not Available
Acute hepatic failure09.01.03.001--Not Available
Acute leukaemia01.10.02.001; Available
Acute myeloid leukaemia16.01.05.001; Available
Acute myocardial infarction24.04.04.001; Available
Acute pulmonary oedema22.01.03.005; Available
Acute respiratory failure14.01.04.004; Available
Addison's disease10.04.08.008;; Available
Adrenal insufficiency14.11.01.004;
Ageusia17.02.07.001; Available
Alanine aminotransferase increased13.03.01.0030.016181%
Altered state of consciousness19.07.01.003; Available
Amylase increased13.05.01.0090.002206%
Anaphylactic reaction24.06.03.006;
Angina pectoris24.04.04.002;
Angioedema23.04.01.001; Available
Aortic dissection24.02.03.0020.000767%Not Available
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