Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Soft tissue sarcoma
ADR ID BADD_A09287
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.09      Musculoskeletal and connective tissue neoplasms
15.09.03      Malignant musculoskeletal and connective tissue neoplasms
15.09.03.021      Soft tissue sarcoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.33      Soft tissue neoplasms malignant and unspecified
16.33.01      Soft tissue sarcomas histology unspecified
16.33.01.003      Soft tissue sarcoma
Description A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. [MeSH]
MedDRA Code 10075333
MeSH ID D012509
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Malignant neoplasm of connective and other soft tissue | Malignant neoplasm of connective and other soft tissue of abdomen | Malignant neoplasm of connective and other soft tissue of head, face, and neck | Malignant neoplasm of connective and other soft tissue of lower limb, including hip | Malignant neoplasm of connective and other soft tissue of pelvis | Malignant neoplasm of connective and other soft tissue of thorax | Malignant neoplasm of connective and other soft tissue of trunk, unspecified | Malignant neoplasm of connective and other soft tissue of upper limb, including shoulder | Malignant neoplasm of connective and other soft tissue, site unspecified | Malignant neoplasm of other specified sites of connective and other soft tissue | Malignant soft tissue neoplasm NOS | Malignant soft tissue neoplasm | Soft tissue cancer | Soft tissue sarcoma | Retroperitoneal sarcoma | Non-rhabdomyosarcoma soft-tissue sarcoma | Sarcoma | Sarcomas | Sarcoma, Soft Tissue | Sarcomas, Soft Tissue | Soft Tissue Sarcoma | Soft Tissue Sarcomas | Sarcoma, Epithelioid | Epithelioid Sarcoma | Epithelioid Sarcomas | Sarcomas, Epithelioid | Sarcoma, Spindle Cell | Sarcomas, Spindle Cell | Spindle Cell Sarcoma | Spindle Cell Sarcomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00723Doxorubicin0.000392%
BADD_D01133Ifosfamide0.000280%
BADD_D01654Palbociclib0.000246%
BADD_D01687Pazopanib0.001959%
BADD_D01834Prednisone0.000018%
BADD_D02100Sunitinib0.001880%
BADD_D02236Tofacitinib0.000241%
BADD_D02253Trabectedin0.000112%
BADD_D02526Larotrectinib0.000112%
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