Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Frontotemporal dementia
ADR ID BADD_A09005
ADR Hierarchy
17      Nervous system disorders
17.03      Mental impairment disorders
17.03.01      Dementia (excl Alzheimer's type)
17.03.01.007      Frontotemporal dementia
19      Psychiatric disorders
19.20      Dementia and amnestic conditions
19.20.02      Dementia NEC
19.20.02.008      Frontotemporal dementia
Description The most common clinical form of FRONTOTEMPORAL LOBAR DEGENERATION, this dementia presents with personality and behavioral changes often associated with disinhibition, apathy, and lack of insight. [MeSH]
MedDRA Code 10068968
MeSH ID D057180; D020774; D057180
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Dementia due to Pick's disease | Frontal lobe syndrome | Pick's disease | Frontotemporal dementia | Frontotemporal Dementia | Dementias, Frontotemporal | Frontotemporal Dementias | Frontotemporal Dementia with Parkinsonism | Dementia, Frontotemporal, with Parkinsonism | Multiple System Tauopathy with Presenile Dementia | Frontotemporal Dementia, Ubiquitin-Positive | Dementia, Ubiquitin-Positive Frontotemporal | Dementias, Ubiquitin-Positive Frontotemporal | Frontotemporal Dementia, Ubiquitin Positive | Frontotemporal Dementias, Ubiquitin-Positive | Ubiquitin-Positive Frontotemporal Dementia | Ubiquitin-Positive Frontotemporal Dementias | Dementia, Hereditary Dysphasic Disinhibition | Dementia, Frontotemporal | Frontotemporal Lobe Dementia | Dementia, Frontotemporal Lobe | Dementias, Frontotemporal Lobe | Frontotemporal Lobe Dementias | Lobe Dementia, Frontotemporal | Lobe Dementias, Frontotemporal | Wilhelmsen-Lynch Disease | Disease, Wilhelmsen-Lynch | Diseases, Wilhelmsen-Lynch | Wilhelmsen Lynch Disease | Wilhelmsen-Lynch Diseases | Frontotemporal Lobar Degeneration With Ubiquitin-Positive Inclusions | Frontotemporal Lobar Degeneration With Ubiquitin Positive Inclusions | Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex | Complex, Disinhibition-Dementia-Parkinsonism-Amyotrophy | Complices, Disinhibition-Dementia-Parkinsonism-Amyotrophy | Disinhibition Dementia Parkinsonism Amyotrophy Complex | Disinhibition-Dementia-Parkinsonism-Amyotrophy Complices | Frontotemporal Dementia with Parkinsonism-17 | Frontotemporal Dementia with Parkinsonism 17 | Disinhibition-Dementia-Parkinsonism-Amytrophy Complex | Complex, Disinhibition-Dementia-Parkinsonism-Amytrophy | Complices, Disinhibition-Dementia-Parkinsonism-Amytrophy | Disinhibition Dementia Parkinsonism Amytrophy Complex | Disinhibition-Dementia-Parkinsonism-Amytrophy Complices | Familial Pick's Disease | Disease, Familial Pick's | Diseases, Familial Pick's | Familial Pick Disease | Familial Pick's Diseases | Familial Picks Disease | Pick's Disease, Familial | Pick's Diseases, Familial | Hereditary Dysphasic Disinhibition Dementia | FTDP-17 | DDPAC | GRN-Related Frontotemporal Dementia | Dementia, GRN-Related Frontotemporal | Dementias, GRN-Related Frontotemporal | Frontotemporal Dementia, GRN-Related | Frontotemporal Dementias, GRN-Related | GRN Related Frontotemporal Dementia | GRN-Related Frontotemporal Dementias | FTD-GRN | FTD-PGRN | FTLD-17 GRN | FTLD with TDP-43 Pathology | FTLD with TDP 43 Pathology | FTLD-TDP | HDDD1 | HDDD2 | Frontotemporal Lobe Dementia (FLDEM) | Dementia, Frontotemporal Lobe (FLDEM) | Dementias, Frontotemporal Lobe (FLDEM) | Frontotemporal Lobe Dementias (FLDEM) | Semantic Dementia | Dementia, Semantic | Dementias, Semantic | Semantic Dementias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00356Carbamazepine0.001263%
BADD_D00474Cisplatin0.000533%
BADD_D00511Clozapine0.005605%
BADD_D00706Donepezil0.000818%
BADD_D01507Mycophenolate mofetil0.001308%
BADD_D01909Ramipril0.000400%
BADD_D01951Risperidone0.001073%
BADD_D02346Venlafaxine0.000149%
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