| ADR Ontology |
| ADR Term |
Astrocytoma, low grade |
| ADR ID |
BADD_A08818 |
| ADR Hierarchy |
|
| Description |
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) [MeSH] |
| MedDRA Code |
10065869 |
| MeSH ID |
D001254
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|
ADR Severity Grade (FAERS)
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|
|
ADR Severity Grade (CTCAE)
|
Not Available
|
| Synonym |
| Cerebral astrocytoma, low grade | Juvenile pilocytic astrocytoma | Astrocytoma, low grade | Fibrillary astrocytoma | Subependymal giant cell astrocytoma | Astrocytoma | Astrocytomas | Astroglioma | Astrogliomas | Glioma, Astrocytic | Astrocytic Glioma | Astrocytic Gliomas | Gliomas, Astrocytic | Astrocytoma, Grade I | Astrocytomas, Grade I | Grade I Astrocytoma | Grade I Astrocytomas | Astrocytoma, Grade II | Astrocytomas, Grade II | Grade II Astrocytoma | Grade II Astrocytomas | Astrocytoma, Protoplasmic | Astrocytomas, Protoplasmic | Protoplasmic Astrocytoma | Protoplasmic Astrocytomas | Astrocytoma, Subependymal Giant Cell | Subependymal Giant Cell Astrocytoma | Pilocytic Astrocytoma | Astrocytoma, Pilocytic | Astrocytomas, Pilocytic | Pilocytic Astrocytomas | Childhood Cerebral Astrocytoma | Astrocytoma, Childhood Cerebral | Astrocytomas, Childhood Cerebral | Cerebral Astrocytoma, Childhood | Cerebral Astrocytomas, Childhood | Childhood Cerebral Astrocytomas | Fibrillary Astrocytoma | Astrocytoma, Fibrillary | Astrocytomas, Fibrillary | Fibrillary Astrocytomas | Gemistocytic Astrocytoma | Astrocytoma, Gemistocytic | Astrocytomas, Gemistocytic | Gemistocytic Astrocytomas | Intracranial Astrocytoma | Astrocytoma, Intracranial | Astrocytomas, Intracranial | Intracranial Astrocytomas | Juvenile Pilocytic Astrocytoma | Astrocytoma, Juvenile Pilocytic | Astrocytomas, Juvenile Pilocytic | Juvenile Pilocytic Astrocytomas | Pilocytic Astrocytoma, Juvenile | Pilocytic Astrocytomas, Juvenile | Oligoastrocytoma, Mixed | Mixed Oligoastrocytoma | Mixed Oligoastrocytomas | Oligoastrocytomas, Mixed | Anaplastic Astrocytoma | Anaplastic Astrocytomas | Astrocytoma, Anaplastic | Astrocytomas, Anaplastic | Astrocytoma, Grade III | Astrocytomas, Grade III | Grade III Astrocytoma | Grade III Astrocytomas | Cerebral Astrocytoma | Astrocytoma, Cerebral | Astrocytomas, Cerebral | Cerebral Astrocytomas |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
|
| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D00364 | Carboplatin | 0.000799% | | | BADD_D00858 | Everolimus | 0.001460% | | | BADD_D02257 | Trametinib | 0.000533% | |
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