Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Atrioventricular septal defect
ADR ID BADD_A08713
ADR Hierarchy
02      Cardiac disorders
02.04      Myocardial disorders
02.04.02      Myocardial disorders NEC
02.04.02.029      Atrioventricular septal defect
03      Congenital, familial and genetic disorders
03.07      Cardiac and vascular disorders congenital
03.07.02      Cardiac septal defects congenital
03.07.02.005      Atrioventricular septal defect
Description A spectrum of septal defects involving the ATRIAL SEPTUM; VENTRICULAR SEPTUM; and the atrioventricular valves (TRICUSPID VALVE; BICUSPID VALVE). These defects are due to incomplete growth and fusion of the ENDOCARDIAL CUSHIONS which are important in the formation of two atrioventricular canals, site of future atrioventricular valves. [MeSH]
MedDRA Code 10063836
MeSH ID D004694
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Endocardial cushion defect NOS | Endocardial cushion defect, unspecified type | Endocardial cushion defects | Other endocardial cushion defects | Atrioventricular canal | Atrioventricular septal defect | Endocardial Cushion Defects | Cushion Defect, Endocardial | Cushion Defects, Endocardial | Defect, Endocardial Cushion | Defects, Endocardial Cushion | Endocardial Cushion Defect | Persistent Common Atrioventricular Canal
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00285Bosentan0.000175%
BADD_D00475Citalopram0.000208%
BADD_D00511Clozapine0.005605%
BADD_D00809Escitalopram0.000074%
BADD_D00932Fluoxetine0.000272%
BADD_D00952Folic acid0.000235%
BADD_D01242Lamivudine0.009276%
BADD_D01418Methotrexate0.000560%
BADD_D01507Mycophenolate mofetil0.001308%
BADD_D01533Naproxen0.000082%
BADD_D01599Olanzapine0.001623%
BADD_D01617Ondansetron0.000200%
BADD_D01627Oseltamivir0.000145%
BADD_D01679Paroxetine0.000467%
BADD_D01762Phenylephrine0.006074%
BADD_D02010Sertraline0.000121%
BADD_D02346Venlafaxine0.000447%
The 1th Page    1    Total 1 Pages