Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Non-small cell lung cancer
ADR ID BADD_A06004
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.19      Respiratory and mediastinal neoplasms malignant and unspecified
16.19.01      Non-small cell neoplasms malignant of the respiratory tract cell type specified
16.19.01.001      Non-small cell lung cancer
22      Respiratory, thoracic and mediastinal disorders
22.08      Respiratory tract neoplasms
22.08.01      Lower respiratory tract neoplasms
22.08.01.002      Non-small cell lung cancer
Description A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. [MeSH]
MedDRA Code 10061873
MeSH ID D002289
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Non-small cell lung cancer NOS | Non-small cell lung cancer | Progression of non-small cell lung cancer | Carcinoma, Non-Small-Cell Lung | Carcinoma, Non Small Cell Lung | Carcinomas, Non-Small-Cell Lung | Lung Carcinoma, Non-Small-Cell | Lung Carcinomas, Non-Small-Cell | Non-Small-Cell Lung Carcinomas | Nonsmall Cell Lung Cancer | Non-Small-Cell Lung Carcinoma | Non Small Cell Lung Carcinoma | Carcinoma, Non-Small Cell Lung | Non-Small Cell Lung Cancer
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib0.001529%
BADD_D00157Aprepitant--
BADD_D00364Carboplatin0.001807%
BADD_D00414Ceritinib0.002849%
BADD_D00511Clozapine--
BADD_D00535Crizotinib0.007645%
BADD_D00564Dabigatran etexilate--
BADD_D00623Dexamethasone0.000179%
BADD_D00800Erlotinib0.000764%
BADD_D00914Fludarabine0.000139%
BADD_D01009Gemcitabine0.000139%
BADD_D01243Lamotrigine0.000067%
BADD_D01253Lenalidomide--
BADD_D01629Osimertinib0.000278%
BADD_D01653Paclitaxel0.001112%
BADD_D01783Pirfenidone0.000302%
BADD_D01834Prednisone0.000010%
BADD_D01835Pregabalin--
BADD_D01954Rivaroxaban--
BADD_D02192Thalidomide0.000302%
BADD_D02363Vinorelbine0.000139%
BADD_D02464Fingolimod--
BADD_D02470Nintedanib0.000278%
BADD_D02480Alectinib0.000347%
BADD_D02509Brigatinib0.000764%
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