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ADR Term
ADReCS ID
MedDRA Code
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ADR Ontology
ADR Term
Skin wrinkling
ADR ID
BADD_A04064
ADR Hierarchy
23
Skin and subcutaneous tissue disorders
23.01
Cornification and dystrophic skin disorders
23.01.03
Skin dystrophies
23.01.03.001
Skin wrinkling
Description
The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight. [MeSH]
MedDRA Code
10040954
MeSH ID
D015595
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Skin wrinkling | Wrinkles | Wrinkling | Glabellar frown lines | Frown lines | Crow's feet | Skin Aging | Aging, Skin | Solar Aging of Skin | Photoaging of Skin | Skin Wrinkling | Skin Wrinklings | Wrinkling, Skin
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Not Available
Not Available
Not Available
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00156
Apremilast
0.004053%
BADD_D00551
Cyclosporine
0.000519%
BADD_D00898
Finasteride
0.000321%
BADD_D01213
Isotretinoin
0.001894%
BADD_D01253
Lenalidomide
0.004053%
BADD_D01709
Penicillamine
-
-
BADD_D01799
Ponatinib
0.000799%
BADD_D01802
Porfimer
-
-
BADD_D01803
Porfimer sodium
-
-
BADD_D01933
Ribavirin
0.018131%
BADD_D02098
Sumatriptan
-
-
BADD_D02099
Sumatriptan succinate
-
-
BADD_D02223
Tiopronin
-
-
BADD_D02236
Tofacitinib
0.001158%
BADD_D02394
Zolpidem
-
-
BADD_D02395
Zolpidem tartrate
-
-
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