Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Leiomyoma
ADR ID BADD_A02497
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.09      Musculoskeletal and connective tissue neoplasms
15.09.02      Musculoskeletal and connective tissue neoplasms NEC
15.09.02.002      Leiomyoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.18      Soft tissue neoplasms benign
16.18.01      Soft tissue neoplasms benign NEC
16.18.01.003      Leiomyoma
Description A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues. [MeSH]
MedDRA Code 10024184
MeSH ID D007889; D007889; D018230; D007889; D018229; D007889; D009214; D007889; D047708
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Leiomyoma | Leiomyoma NOS | Epithelioid leiomyoma | Leiomyoblastoma | Angioleiomyoma | Myoma | Myofibroma | Leiomyomas | Fibroid Tumor | Fibroid Tumors | Tumor, Fibroid | Tumors, Fibroid | Fibromyoma | Fibromyomas | Fibroid | Fibroids | Fibroid Uterus | Uterus, Fibroid | Fibroma, Uterine | Fibromas, Uterine | Uterine Fibroma | Uterine Fibromas | Fibroids, Uterine | Fibroid, Uterine | Uterine Fibroid | Uterine Fibroids | Leiomyoma, Uterine
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Catenin beta-1P35222T82795
Proto-oncogene Wnt-1P04628Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00680Dimethyl fumarate0.002751%
BADD_D01250Lasofoxifene--
BADD_D01281Levonorgestrel0.003127%
BADD_D02464Fingolimod0.001737%
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