Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Lactase deficiency
ADR ID BADD_A02469
ADR Hierarchy
07      Gastrointestinal disorders
07.17      Malabsorption conditions
07.17.01      Malabsorption syndromes
07.17.01.006      Lactase deficiency
14      Metabolism and nutrition disorders
14.02      Food intolerance syndromes
14.02.02      Sugar intolerance (excl glucose intolerance)
14.02.02.003      Lactase deficiency
Description The condition resulting from the absence or deficiency of LACTASE in the MUCOSA cells of the GASTROINTESTINAL TRACT, and the inability to break down LACTOSE in milk for ABSORPTION. Bacterial fermentation of the unabsorbed lactose leads to symptoms that range from a mild indigestion (DYSPEPSIA) to severe DIARRHEA. Lactose intolerance may be an inborn error or acquired. [MeSH]
MedDRA Code 10023648
MeSH ID D007787
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Alactasia | Lactase deficiency | Lactose Intolerance | Intolerance, Lactose | Hypolactasia | Milk Sugar Intolerance | Lactose Malabsorption | Malabsorption, Lactose | Dairy Product Intolerance
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00518Colchicine--
BADD_D00774Entecavir--
BADD_D01966Ropinirole--
BADD_D02379Zaleplon--
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