Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypospadias
ADR ID BADD_A02214
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.03      Reproductive tract and breast disorders congenital
03.03.01      Male reproductive tract disorders congenital
03.03.01.005      Hypospadias
20      Renal and urinary disorders
20.07      Urethral disorders (excl calculi)
20.07.04      Congenital urethral disorders
20.07.04.001      Hypospadias
21      Reproductive system and breast disorders
21.15      Congenital reproductive tract and breast disorders
21.15.01      Congenital male reproductive tract disorders
21.15.01.003      Hypospadias
Description A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA. [MeSH]
MedDRA Code 10021093
MeSH ID D007021
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypospadias | Hypospadias and epispadias | Hypospadia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00129Amoxicillin0.000020%
BADD_D00356Carbamazepine0.002947%
BADD_D00475Citalopram0.000791%
BADD_D00498Clomiphene citrate--
BADD_D00595Deferiprone--
BADD_D00809Escitalopram0.000332%
BADD_D00912Fluconazole0.000206%
BADD_D00932Fluoxetine0.000454%
BADD_D00952Folic acid0.000353%
BADD_D00981Gabapentin0.000127%
BADD_D01136Imatinib0.000533%
BADD_D01242Lamivudine0.004638%
BADD_D01243Lamotrigine0.000403%
BADD_D01265Levetiracetam0.002095%
BADD_D01353Mebendazole0.036077%
BADD_D01380Menotropins--
BADD_D01401Metformin0.000037%
BADD_D01445Metoprolol0.000140%
BADD_D01476Mirtazapine0.000365%
BADD_D01599Olanzapine0.001082%
BADD_D01617Ondansetron0.000350%
BADD_D01627Oseltamivir0.000217%
BADD_D01679Paroxetine0.001402%
BADD_D01852Progesterone--
BADD_D02010Sertraline0.000574%
BADD_D02155Tenofovir disoproxil0.013329%
BADD_D02247Topiramate0.001794%
BADD_D02329Valproic acid0.007086%
BADD_D02346Venlafaxine0.000224%
BADD_D02394Zolpidem0.000109%
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