Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypertrophy
ADR ID BADD_A02166
ADR Hierarchy
08      General disorders and administration site conditions
08.03      Tissue disorders NEC
08.03.04      Trophic disorders
08.03.04.005      Hypertrophy
Description General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). [MeSH]
MedDRA Code 10020880
MeSH ID D006984
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypertrophy | Hypertrophy NOS | Hypertrophies
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Glutathione hydrolase 1 proenzymeP19440Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000404%
BADD_D00086Alprostadil--
BADD_D00294Brimonidine--
BADD_D00576Danazol--
BADD_D00623Dexamethasone0.000687%
BADD_D00706Donepezil--
BADD_D00898Finasteride0.000214%
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
BADD_D01322Losartan--
BADD_D01530Nandrolone decanoate--
BADD_D01617Ondansetron0.000100%
BADD_D02011Sertraline hydrochloride--
BADD_D02236Tofacitinib0.003474%
BADD_D02392Zoledronic acid0.013122%
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