Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Gastroduodenal ulcer
ADR ID BADD_A01742
ADR Hierarchy
07      Gastrointestinal disorders
07.04      Gastrointestinal ulceration and perforation
07.04.02      Duodenal ulcers and perforation
07.04.02.005      Gastroduodenal ulcer
Description Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). | A well-known complication of GASTROENTEROSTOMY. These ulcers occur at the gastrojejunal anastomosis, mostly on the jejunal side. [MeSH]
MedDRA Code 10017886
MeSH ID D010437
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Gastroduodenal ulcer | GDU | Ulcer gastroduodenal | Peptic Ulcer | Peptic Ulcers | Ulcer, Peptic | Ulcers, Peptic | Gastroduodenal Ulcer | Gastroduodenal Ulcers | Ulcer, Gastroduodenal | Ulcers, Gastroduodenal | Marginal Ulcer | Marginal Ulcers | Ulcer, Marginal | Ulcers, Marginal
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00065Alendronate sodium--
BADD_D00329Cabergoline--
BADD_D01009Gemcitabine0.000533%
BADD_D01835Pregabalin0.000236%
BADD_D02373Warfarin0.000120%
BADD_D02396Zonisamide--
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