Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bronchopulmonary dysplasia
ADR ID BADD_A00718
ADR Hierarchy
18      Pregnancy, puerperium and perinatal conditions
18.04      Neonatal and perinatal conditions
18.04.10      Neonatal respiratory distress related conditions
18.04.10.001      Bronchopulmonary dysplasia
22      Respiratory, thoracic and mediastinal disorders
22.11      Neonatal respiratory disorders
22.11.01      Newborn respiratory disorders NEC
22.11.01.001      Bronchopulmonary dysplasia
Description A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS. [MeSH]
MedDRA Code 10006475
MeSH ID D001997
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bronchopulmonary dysplasia | Chronic lung disease of prematurity | Bronchopulmonary Dysplasia | Dysplasia, Bronchopulmonary
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00285Bosentan0.000292%
BADD_D00932Fluoxetine0.000047%
BADD_D01120Ibuprofen0.000423%
BADD_D01156Indomethacin0.000942%
BADD_D01318Lorazepam0.000035%
BADD_D01617Ondansetron0.000026%
BADD_D01679Paroxetine0.000049%
BADD_D01801Poractant alfa--
BADD_D02010Sertraline0.000047%
BADD_D02429Clomifene0.001364%
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