Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etelcalcetide
Drug ID BADD_D02514
Description Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Indications and Usage Etelcalcetide is a calcium-sensing receptor agonist indicated for: Secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis.
Marketing Status Not Available
ATC Code H05BX04
DrugBank ID DB12865
KEGG ID D10676
MeSH ID C583569
PubChem ID 71511839
NDC Product Code 55513-740; 55463-0030; 52076-6227; 55513-742; 55513-741
Synonyms etelcalcetide hydrochloride | velcalcetide | etelcalcetide | KAI-4169 | Parsabiv | AMG-416 | AMG 416
Chemical Information
Molecular Formula C38H73N21O10S2
CAS Registry Number 1262780-97-1
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.038552%Not Available
Abdominal pain07.01.05.0020.028914%
Abdominal pain upper07.01.05.003--
Abnormal dreams19.02.03.001; Available
Angina pectoris24.04.04.002;
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Bile duct stone09.02.02.0030.007228%Not Available
Blood albumin decreased13.09.01.0010.004819%Not Available
Blood calcium abnormal13.11.01.0220.038552%Not Available
Blood calcium decreased13.11.01.0020.156616%Not Available
Blood calcium increased13.11.01.0030.024095%Not Available
Blood parathyroid hormone increased13.10.07.0020.051542%Not Available
Blood potassium increased13.11.01.0110.012047%Not Available
Blood pressure decreased13.14.03.0020.012047%Not Available
Blood pressure increased13.14.03.0050.016866%Not Available
Bone pain15.02.01.0010.021685%
Cardiac arrest02.03.04.0010.004400%
Cardiac failure02.05.01.0010.008800%
Cardiac failure acute02.05.01.0050.001257%Not Available
Cardiac failure congestive02.05.01.002--Not Available
Cardiovascular disorder24.03.02.009; Available
Cerebral haemorrhage24.07.04.001; Available
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