Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Metamfetamine
Drug ID BADD_D02444
Description Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug. It is a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse.
Indications and Usage For the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity.
Marketing Status Not Available
ATC Code N06BA03
DrugBank ID DB01577
KEGG ID D08187
MeSH ID D008694
PubChem ID 10836
TTD Drug ID D0P6UB
NDC Product Code Not Available
Synonyms Methamphetamine | Desoxyephedrine | Metamfetamine | Methylamphetamine | N-Methylamphetamine | N Methylamphetamine | Deoxyephedrine | Desoxyn | Madrine | Methamphetamine Hydrochloride | Hydrochloride, Methamphetamine
Chemical Information
Molecular Formula C10H15N
CAS Registry Number 537-46-2
SMILES CC(CC1=CC=CC=C1)NC
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aggression19.05.01.0010.000290%Not Available
Blood creatinine increased13.13.01.0040.000290%
Cardiac arrest02.03.04.0010.000151%
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.000378%Not Available
Choreoathetosis17.01.01.0030.000724%Not Available
Completed suicide19.12.01.001; 08.04.01.0100.000151%Not Available
Crying12.02.11.001; 08.01.03.005; 19.04.02.002; 17.02.05.0130.000434%Not Available
Death08.04.01.0010.000264%
Developmental delay08.01.03.0370.000434%Not Available
Drug abuse19.07.02.0100.000453%Not Available
Drug withdrawal syndrome neonatal19.07.02.012; 18.04.13.001; 08.06.02.0080.000434%Not Available
Encephalopathy17.13.02.0010.000434%
Hyperammonaemia14.10.01.001; 09.01.02.0020.000434%Not Available
Irritability19.04.02.013; 08.01.03.0110.000434%
Metabolic acidosis14.01.01.0030.000290%Not Available
Premature baby18.04.02.0010.000290%Not Available
Respiratory arrest22.02.01.0090.000076%Not Available
Sinus tachycardia02.03.03.0100.000290%
Somnolence19.02.05.003; 17.02.04.0060.000290%
Tachypnoea22.02.01.0140.000724%Not Available
Tremor17.01.06.0020.000434%
Pulmonary arterial hypertension24.08.03.003; 22.06.01.0020.000113%Not Available
Substance abuse19.07.02.0060.000434%Not Available
Low birth weight baby18.04.02.0030.000290%Not Available
Foetal growth restriction18.03.01.0020.000290%
Substance-induced psychotic disorder19.03.01.007; 12.03.01.0530.000290%Not Available
Poor sucking reflex18.04.04.011; 17.02.01.0080.000434%Not Available
Selective eating disorder19.09.01.012; 14.03.02.0240.000434%Not Available
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