Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Magnesium oxide
Drug ID BADD_D02442
Description Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Indications and Usage Magnesium hydroxide is used as a laxative to relieve occasional constipation (irregularity) and as an antacid to relieve indigestion, sour stomach, and heartburn.
Marketing Status Not Available
ATC Code A02AA02; A06AD02; A12CC10
DrugBank ID DB01377
KEGG ID D01167
MeSH ID D008277
PubChem ID 14792
TTD Drug ID Not Available
NDC Product Code 71335-1960; 0603-0209; 58657-120; 63629-2217; 63629-1126; 50917-877; 55570-280; 69367-298; 0603-0213; 50917-837; 68210-4171; 71610-182; 54738-974; 71610-172; 50917-857; 54738-973; 50917-867; 12784-437; 50917-887
Synonyms Magnesium Oxide | Oxide, Magnesium | Magnesia
Chemical Information
Molecular Formula MgO
CAS Registry Number 1309-48-4
SMILES O=[Mg]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.000877%
Altered state of consciousness17.02.04.001; 19.07.01.0030.000877%Not Available
Anaemia01.03.02.0010.001461%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.000584%
Arrhythmia02.03.02.0010.000584%Not Available
Asthenia08.01.01.0010.000584%Not Available
Blood creatine phosphokinase increased13.04.01.0010.000584%
Blood pressure decreased13.14.03.0020.000229%Not Available
Breast cancer21.05.01.003; 16.10.01.0010.000152%Not Available
C-reactive protein increased13.09.01.0070.000584%Not Available
Cerebral infarction24.04.06.002; 17.08.01.0040.000229%Not Available
Chills15.05.03.016; 08.01.09.0010.000584%
Coma17.02.09.0010.000584%Not Available
Constipation07.02.02.0010.001461%
Death08.04.01.001--
Dehydration14.05.05.0010.000584%
Depressed level of consciousness17.02.04.0020.000877%
Depression19.15.01.0010.000584%
Diarrhoea07.02.01.0010.003215%
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.001169%
Dry mouth07.06.01.0020.000877%
Dysphagia07.01.06.0030.001169%
Dyspnoea22.02.01.004; 02.01.03.002--
Headache17.14.01.001--
Hepatic failure09.01.03.0020.000152%
Hepatic function abnormal09.01.02.0010.001169%Not Available
Hepatitis fulminant11.07.01.003; 09.01.07.0070.000152%Not Available
Hypercalcaemia14.04.01.003; 05.04.01.0020.000584%
Hyperhidrosis23.02.03.004; 08.01.03.0280.000584%
Hypermagnesaemia14.04.02.0020.007306%
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