Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Enoxaparin
Drug ID BADD_D02438
Description Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding.[A228178,A228313]
Indications and Usage For the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
Marketing Status Not Available
ATC Code B01AB01; B01AB12; C05BA03; S01XA14
DrugBank ID DB01225
KEGG ID D07510
MeSH ID D017984
PubChem ID 772
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms Enoxaparin | Enoxaparine | PK-10,169 | PK 10,169 | PK10,169 | PK-10169 | PK 10169 | PK10169 | EMT-967 | EMT 967 | EMT967 | Lovenox | Clexane | EMT-966 | EMT 966 | EMT966
Chemical Information
Molecular Formula C26H42N2O37S5
CAS Registry Number 9005-49-6
SMILES CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C( C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ischaemic hepatitis24.04.07.004; 09.01.07.0180.001574%Not Available
Jaundice09.01.01.004; 01.06.04.004; 23.03.03.0300.004197%Not Available
Joint swelling15.01.02.004--Not Available
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Leukopenia01.02.02.0010.003148%Not Available
Liver disorder09.01.08.0010.002099%Not Available
Loss of consciousness17.02.04.004--Not Available
Lymphadenopathy01.09.01.0020.001574%Not Available
Lymphopenia01.02.02.0020.001574%Not Available
Macule23.03.03.0370.001049%Not Available
Malaise08.01.01.003--
Melaena07.12.02.004; 24.07.02.0130.007870%Not Available
Metrorrhagia21.01.01.0060.002099%Not Available
Muscle haemorrhage24.07.01.037; 15.05.03.0170.012592%Not Available
Muscle spasms15.05.03.004--
Muscular weakness17.05.03.005; 15.05.06.0010.004722%
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Neck pain15.03.04.0090.001574%
Necrosis24.04.02.006; 08.03.03.0010.000547%Not Available
Neoplasm malignant16.16.01.0010.000821%Not Available
Nephrolithiasis20.04.01.0020.001049%
Nephropathy toxic20.05.03.002; 12.03.01.0100.001049%Not Available
Nervous system disorder17.02.10.0010.001574%Not Available
Neurogenic bladder20.03.03.001; 17.10.01.0020.001049%Not Available
Neuropathy peripheral17.09.03.003--Not Available
Neurotoxicity17.02.10.002; 12.03.01.0110.001049%Not Available
Neutropenia01.02.03.0040.015216%Not Available
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