Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methylergometrine
Drug ID BADD_D02417
Description A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Indications and Usage For the prevention and control of excessive bleeding following vaginal childbirth
Marketing Status Not Available
ATC Code G02AB01
DrugBank ID DB00353
KEGG ID D08207
MeSH ID D008755
PubChem ID 8226
TTD Drug ID D05AHE
NDC Product Code Not Available
Synonyms Methylergonovine | Methylergometrine | Methylergobasin | Methylergometrin | Methylergonovine Maleate | Methylergometrine Maleate | Methergine | Méthergin | Methergin
Chemical Information
Molecular Formula C20H25N3O2
CAS Registry Number 113-42-8
SMILES CCC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.010281%
Agitation19.06.02.001; 17.02.05.0120.010281%
Areflexia17.02.01.0010.010281%Not Available
Arteriospasm coronary24.04.04.005; 02.02.02.0050.010281%Not Available
Bradycardia02.03.02.0020.010281%Not Available
Bronchospasm22.03.01.004; 10.01.03.0120.015422%
Crying19.04.02.002; 17.02.05.013; 12.02.11.001; 08.01.03.0050.010281%Not Available
Cyanosis02.01.02.002; 24.03.01.007; 22.02.02.0070.010281%
Death08.04.01.001--
Diarrhoea07.02.01.0010.010281%
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.0070.015422%
Dyspnoea22.02.01.004; 02.01.03.0020.020563%
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.0030.010281%
Headache17.14.01.0010.025704%
Hepatic congestion09.01.05.008; 02.05.04.0130.002682%Not Available
Hyperaesthesia17.02.06.0040.010281%Not Available
Hypercapnia22.02.02.002; 14.01.04.0010.015422%Not Available
Hypertension24.08.02.0010.010281%
Hypertonia17.05.02.001; 15.05.04.0070.020563%Not Available
Hyponatraemia14.05.04.0020.010281%
Hypotension24.06.03.0020.010281%
Irritability19.04.02.013; 08.01.03.0110.010281%
Meningitis aseptic17.06.03.002; 11.01.03.0020.010281%Not Available
Muscle contractions involuntary17.05.03.001; 15.05.03.0080.010281%Not Available
Mydriasis17.02.11.003; 06.05.03.0040.025704%Not Available
Nausea07.01.07.0010.015422%
Opisthotonus17.01.03.0050.010281%Not Available
Pallor23.03.03.031; 08.01.03.032; 24.03.04.0010.015422%Not Available
Respiration abnormal22.02.08.0110.010281%Not Available
Respiratory depression22.02.01.010; 17.02.05.0470.020563%Not Available
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