Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ferric citrate
Drug ID BADD_D02402
Description Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease.[A25965] Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.[L9926]
Indications and Usage Not Available
Marketing Status Not Available
ATC Code V03AE08
DrugBank ID DB14520
KEGG ID D09993
MeSH ID C025314
PubChem ID 61300
TTD Drug ID D04CJL
NDC Product Code 57297-144; 53296-0117; 17511-124; 58159-035; 0792-0046; 65675-1114; 66499-0069; 59922-631
Synonyms ferric citrate | iron(III) citrate | ferric-citric acid | ferric citrate anhydrous | ferric citrate hydrate | JTT-751 | zerenex | ferric citrate trihydrate | ferric citrate, 59Fe-labeled cpd | ferric citrate, iron salt, 59Fe-labeled cpd | ferric citrate dihydrate | ferric citrate iron(+3) salt
Chemical Information
Molecular Formula C6H5FeO7
CAS Registry Number 1185-57-5
SMILES C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Fe+3]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.026240%Not Available
Abdominal distension07.01.04.0010.005831%
Abdominal pain07.01.05.0020.026240%
Abdominal pain upper07.01.05.0030.034987%
Abnormal faeces07.01.03.0010.011662%Not Available
Alopecia23.02.02.001--
Arrhythmia02.03.02.0010.002282%Not Available
Blood iron increased13.11.01.0070.014578%Not Available
Blood potassium increased13.11.01.0110.001521%Not Available
Cardiac arrest02.03.04.0010.013691%
Cardiac failure02.05.01.0010.003803%
Cardiac failure congestive02.05.01.002--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain02.02.02.011; 22.02.08.003; 08.01.08.0020.014578%Not Available
Constipation07.02.02.0010.052481%
Cough22.02.03.001--
Death08.04.01.0010.032705%
Diarrhoea07.02.01.0010.294474%
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dysphagia07.01.06.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Faeces discoloured07.01.03.0020.052481%Not Available
Flatulence07.01.04.0020.008747%
Gangrene11.02.01.003; 24.04.05.003; 23.06.06.0010.001521%Not Available
Gastrointestinal disorder07.11.01.0010.032071%Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.0010.055396%Not Available
Gastrointestinal pain07.01.05.0050.005831%
Haematochezia24.07.02.012; 07.12.02.0030.005831%Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemoglobin increased13.01.05.0040.037903%
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