Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Zanamivir
Drug ID BADD_D02380
Description A guanido-neuraminic acid that is used to inhibit neuraminidase.
Indications and Usage For the prevention and treatment of influenza A and B.
Marketing Status approved; investigational
ATC Code J05AH01
DrugBank ID DB00558
KEGG ID D00902
MeSH ID D053243
PubChem ID 60855
TTD Drug ID D00NPP
NDC Product Code 0173-0681; 63379-028
UNII L6O3XI777I
Synonyms Zanamivir | 2,3-Didehydro-2,4-Dideoxy-4-Guanidinyl-N-Acetylneuraminic Acid | 4-Guanidino-2,4-Dideoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 5-Acetylamino-2,6-Anhydro-4-Guanidino-3,4,5-Trideoxy-D-Galacto-Non-Enoic Acid | 4-Guanidino-Neu5Ac2en | 4 Guanidino Neu5Ac2en | 2,3-Didehydro-2,4-Dideoxy-4-Guanidino-N-Acetyl-D-Neuraminic Acid | 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 4 Guanidino 2 Deoxy 2,3 Didehydro N Acetylneuraminic Acid | Acid, 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic | Relenza | GG 167 | GG167 | GG-167
Chemical Information
Molecular Formula C12H20N4O7
CAS Registry Number 139110-80-8
SMILES CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Influenza like illness08.01.03.010--
Loss of consciousness17.02.04.0040.003020%Not Available
Lung disorder22.02.07.001--Not Available
Lymphopenia01.02.02.002--Not Available
Malaise08.01.01.0030.000565%
Memory impairment19.20.01.003; 17.03.02.0030.001948%
Mental impairment19.21.02.003; 17.03.03.0020.000423%Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.000282%Not Available
Muscular weakness17.05.03.005; 15.05.06.0010.000282%
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
Nasal inflammation22.04.04.002--Not Available
Nausea07.01.07.001--
Neutropenia01.02.03.004--Not Available
Nightmare19.02.03.003--Not Available
Oropharyngeal swelling22.04.05.005; 10.01.05.014; 07.05.04.002; 23.04.01.013--Not Available
Pain08.01.08.004--
Pallor24.03.04.001; 23.03.03.031; 08.01.03.0320.000282%Not Available
Parosmia22.04.03.007; 17.04.04.0020.000621%Not Available
Pericardial effusion02.06.01.0020.000282%
Pharyngeal haemorrhage24.07.02.017; 22.04.05.002--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Phobia19.06.03.0020.000282%Not Available
Pyrexia08.05.02.0030.000988%
Rash23.03.13.001--Not Available
Renal failure20.01.03.0050.000282%Not Available
Respiratory distress22.02.01.0120.000282%Not Available
Respiratory failure22.02.06.002; 14.01.04.0030.001129%
Restlessness19.11.02.002; 17.02.05.0210.000621%
Rhinitis22.07.03.006; 11.01.13.004--
The 3th Page    First    Pre   3 4 5    Next   Last    Total 5 Pages