Pharmaceutical Information |
Drug Name |
Vinblastine sulfate |
Drug ID |
BADD_D02359 |
Description |
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.) |
Indications and Usage |
For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
L01CA01 |
DrugBank ID |
DB00570
|
KEGG ID |
D01068
|
MeSH ID |
D014747
|
PubChem ID |
5388983
|
TTD Drug ID |
D0W9MM
|
NDC Product Code |
53104-7504; 72969-083; 48954-588; 63323-278 |
Synonyms |
Vinblastine | Vincaleukoblastine | Lemblastine | Velban | Vinblastina Lilly | Velbe | Vinblastine Sulfate | Sulfate, Vinblastine | Vinblastinsulfat-Gry | Cellblastin | Vinblastin Hexal |
|
Chemical Information |
Molecular Formula |
C46H58N4O9.H2O4S |
CAS Registry Number |
143-67-9 |
SMILES |
CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8
N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
Chemical Structure |
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ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
|
ADRs Induced by Drug |
ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
Bone marrow failure | 01.03.03.005 | - | - | |
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