Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vinblastine
Drug ID BADD_D02358
Description Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Indications and Usage For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Marketing Status approved
ATC Code L01CA01
DrugBank ID DB00570
KEGG ID D08675
MeSH ID D014747
PubChem ID 13342
TTD Drug ID D0W9MM
NDC Product Code Not Available
UNII 5V9KLZ54CY
Synonyms Vinblastine | Vincaleukoblastine | Lemblastine | Velban | Vinblastina Lilly | Velbe | Vinblastine Sulfate | Sulfate, Vinblastine | Vinblastinsulfat-Gry | Cellblastin | Vinblastin Hexal
Chemical Information
Molecular Formula C46H58N4O9
CAS Registry Number 865-21-4
SMILES CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8 N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.002--
Asthenia08.01.01.001--Not Available
Bone pain15.02.01.001--
Cellulitis23.11.02.004; 11.02.01.001--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Constipation07.02.02.001--
Deafness04.02.01.001--Not Available
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Enterocolitis haemorrhagic24.07.02.006; 07.08.01.007--Not Available
Extravasation08.01.03.008--Not Available
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hypertension24.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Ileus07.13.01.001--
Leukopenia01.02.02.001--Not Available
Malaise08.01.01.003--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Neoplasm16.16.02.001--Not Available
Neuritis17.09.03.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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