Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Valganciclovir hydrochloride
Drug ID BADD_D02327
Description Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Indications and Usage Valganciclovir is an antiviral medication used for the treatment of cytomegalovirus infections.
Marketing Status Prescription
ATC Code J05AB14
DrugBank ID DB01610
KEGG ID D03256
MeSH ID D000077562
PubChem ID 135413534
TTD Drug ID D06GWF
NDC Product Code 63629-2288; 0603-6330; 69875-8044; 17337-0040; 61876-0072; 0004-0039; 65862-756; 42291-875; 63285-852; 65862-753; 65015-818; 65977-0070; 27241-159; 43598-356; 71666-008; 12869-038; 63739-357; 65015-798; 0591-2579; 55111-929; 55111-884; 38779-3065
Synonyms Valganciclovir | Ganciclovir L-valyl Ester | Ganciclovir L valyl Ester | Valcyt | Valganciclovir Hydrochloride | Valcyte
Chemical Information
Molecular Formula C14H23ClN6O5
CAS Registry Number 175865-59-5
SMILES CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vomiting07.01.07.003--
Wound dehiscence12.02.05.003--
Wound drainage25.01.02.007--Not Available
Haemorrhage24.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Postoperative wound complication12.02.05.019--Not Available
Psychotic disorder19.03.01.002--
Renal impairment20.01.03.010--Not Available
Ischaemic limb pain24.04.03.014--Not Available
Procedural pain08.01.08.009; 12.02.05.007--Not Available
Bone marrow failure01.03.03.005--
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