Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ursodiol
Drug ID BADD_D02321
Description Ursodeoxycholic acid is an epimer of [chenodeoxycholic acid]. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.
Indications and Usage The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.
Marketing Status Prescription; Discontinued
ATC Code A05AA02
DrugBank ID DB01586
KEGG ID D00734
MeSH ID D014580
PubChem ID 31401
TTD Drug ID D0G3SH
NDC Product Code 70771-1407; 42806-503; 68462-474; 0591-3159; 46438-0090; 60592-998; 72887-144; 80056-144; 62991-2185; 72789-205; 72664-217; 70771-1524; 55154-3355; 70710-1127; 42385-946; 51552-0906; 63629-2287; 0904-7168; 64380-918; 51927-2909; 80056-143; 22365-012; 63629-8353; 24658-780; 49884-413; 63629-2286; 63629-1048; 51079-383; 64380-919; 70771-1408; 0395-8174; 64980-483; 60687-100; 66039-936; 49884-412; 38779-1987; 69238-1540; 68462-473; 0904-6221; 24658-999; 49452-8085; 58914-790; 63629-1173; 52544-930; 68001-377; 46438-0654; 49345-2612; 64380-844; 0378-1730; 72887-143; 68001-378; 61200-001; 60429-662; 70710-1483; 70710-1128; 50268-797; 0527-1326; 60687-527; 0591-3005; 0591-2998; 46438-0089; 51224-151; 0904-6890; 72969-076; 71930-015; 58914-785; 46438-0653
Synonyms Ursodeoxycholic Acid | Acid, Ursodeoxycholic | Ursacholic Acid | Acid, Ursacholic | 3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid | 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid | Ursodiol | Deoxyursocholic Acid | Acid, Deoxyursocholic | Ursolvan | Delursan | Destolit | Sodium Ursodeoxycholate | Ursodeoxycholate, Sodium | Urdox | Urso | Urso Heumann | Ursobilane | Ursochol | Ursofalk | Ursogal | Ursolite | Cholit-Ursan | Cholofalk
Chemical Information
Molecular Formula C24H40O4
CAS Registry Number 128-13-2
SMILES CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dyspnoea02.01.03.002; 22.02.01.004--
Dysuria20.02.02.002--
Ear disorder04.03.01.001--Not Available
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Epistaxis24.07.01.005; 22.04.03.001--
Eructation07.01.02.003--
Eye disorder06.08.03.001--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Gamma-glutamyltransferase increased13.03.01.011--
Gastric ulcer07.04.03.002--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised oedema08.01.07.004; 14.05.06.007--
Granuloma23.03.15.001; 08.01.05.001--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatic cirrhosis09.01.04.001--Not Available
Hepatic function abnormal09.01.02.001--Not Available
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Hip fracture15.08.03.001; 12.04.01.001--
The 3th Page    First    Pre   3 4 5 6 7    Next   Last    Total 7 Pages