| Pharmaceutical Information |
| Drug Name |
Triptorelin |
| Drug ID |
BADD_D02297 |
| Description |
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. |
| Indications and Usage |
Triptorelin is indicated for the palliative treatment of advanced prostate cancer. |
| Marketing Status |
Prescription |
| ATC Code |
L02AE04 |
| DrugBank ID |
DB06825
|
| KEGG ID |
D06247
|
| MeSH ID |
D017329
|
| PubChem ID |
25074470
|
| TTD Drug ID |
D03QRS
|
| NDC Product Code |
71161-106; 24338-150 |
| Synonyms |
Triptorelin Pamoate | Pamoate, Triptorelin | Triptorelin Embonate | Embonate, Triptorelin | CL-118532 | CL 118532 | CL118532 | Trelstar | Triptorelin | LHRH, Trp(6)- | GnRH, Trp(6)- | LHRH, Tryptophyl(6)- | D-Trp-6-LH-RH | 6-D-Tryptophan-Luteinizing Hormone-Releasing Factor (Pig) | Wy-42462 | Wy 42462 | Wy42462 | AY-25650 | AY 25650 | AY25650 | Decapeptyl | Decapeptyl Trimestral | Trimestral, Decapeptyl | Decapeptyl LP | Decapeptyl Depot |
|
| Chemical Information |
| Molecular Formula |
C64H82N18O13 |
| CAS Registry Number |
57773-63-4 |
| SMILES |
CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)
NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7
)NC(=O)C8CCC(=O)N8 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
