Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triazolam
Drug ID BADD_D02277
Description Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Indications and Usage For the short-term treatment of insomnia.
Marketing Status approved; investigational
ATC Code N05CD05
DrugBank ID DB00897
KEGG ID D00387
MeSH ID D014229
PubChem ID 5556
TTD Drug ID D0U3LS
NDC Product Code 12828-0041; 0009-0017; 50090-6471; 59762-3717; 43353-451; 70710-1521; 71335-1876; 0009-5188; 42816-0017; 67763-128; 0054-4858; 50742-645; 43063-996; 50742-646; 59762-3718; 70710-1289; 70771-1576; 50090-4733; 70771-1162; 0054-4859
UNII 1HM943223R
Synonyms Triazolam | U-33,030 | U 33,030 | U33,030 | Halcion | Trilam | Apo-Triazo | Apo Triazo | Gen-Triazolam | Gen Triazolam
Chemical Information
Molecular Formula C17H12Cl2N4
CAS Registry Number 28911-01-5
SMILES CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin ulcer24.04.03.007; 23.07.03.0030.000403%
Sleep disorder19.02.04.001--Not Available
Somnambulism19.02.03.006; 17.15.02.0040.000403%Not Available
Somnolence17.02.04.006; 19.02.05.0030.006084%
Speech disorder17.02.08.003; 22.12.03.027; 19.19.02.0020.000604%Not Available
Stomatitis07.05.06.005--
Strangury20.02.02.017--Not Available
Stupor19.02.05.004; 17.02.04.0070.000806%Not Available
Suicidal ideation19.12.01.0030.001007%
Suicide attempt19.12.01.0040.005036%
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.000806%
Tachycardia02.03.02.0070.000806%Not Available
Tension19.06.02.005--Not Available
Therapeutic response decreased08.06.01.016--Not Available
Thinking abnormal19.10.03.001; 17.02.05.023--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Tremor17.01.06.0020.000604%
Urinary incontinence20.02.02.010; 17.05.01.0080.000403%
Urinary retention20.02.02.0110.000604%
Vertigo17.02.12.002; 04.04.01.0030.000403%
Vision blurred17.17.01.010; 06.02.06.007--
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
White blood cell count13.01.06.027--Not Available
Withdrawal syndrome19.07.06.023; 08.06.02.0120.000806%Not Available
Hypoacusis04.02.01.006--
Paradoxical drug reaction08.06.01.014--Not Available
Basophil count13.01.06.042--Not Available
Balance disorder08.01.03.081; 17.02.02.007--Not Available
Bradyphrenia19.10.03.002; 17.03.03.0040.002417%Not Available
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