Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triazolam
Drug ID BADD_D02277
Description Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Indications and Usage For the short-term treatment of insomnia.
Marketing Status Prescription; Discontinued
ATC Code N05CD05
DrugBank ID DB00897
KEGG ID D00387
MeSH ID D014229
PubChem ID 5556
TTD Drug ID D0U3LS
NDC Product Code 0009-0017; 55289-787; 67763-128; 0054-4858; 0009-5188; 50742-645; 59762-3718; 50742-646; 71335-1876; 59762-3717; 50090-4733; 12828-0041; 0054-4859; 43063-996; 50090-0522; 42816-0017; 43353-451; 63629-2956
Synonyms Triazolam | U-33,030 | U 33,030 | U33,030 | Halcion | Trilam | Apo-Triazo | Apo Triazo | Gen-Triazolam | Gen Triazolam
Chemical Information
Molecular Formula C17H12Cl2N4
CAS Registry Number 28911-01-5
SMILES CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuroleptic malignant syndrome12.03.01.003; 08.05.01.005; 17.05.02.003; 15.05.04.0150.001847%Not Available
Neutrophil count13.01.06.046--Not Available
Nightmare19.02.03.003--Not Available
Non-cardiogenic pulmonary oedema24.03.08.004; 22.01.03.0060.002770%Not Available
Oedema08.01.07.006; 14.05.06.0100.001847%Not Available
Osteoarthritis15.01.04.001--Not Available
Pain08.01.08.004--
Palpitations02.01.02.0030.001847%
Pancreatitis07.18.01.0010.001847%
Paraesthesia17.02.06.005--
Platelet count decreased13.01.04.0010.001847%
Pneumonia aspiration22.01.01.0050.000482%Not Available
Presyncope24.06.02.010; 17.02.05.009; 02.01.02.0070.002770%
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Red blood cell count13.01.05.020--Not Available
Respiratory arrest22.02.01.0090.000723%Not Available
Restlessness17.02.05.021; 19.11.02.0020.001847%
Rhabdomyolysis15.05.05.0020.001847%
Sedation17.02.04.005--Not Available
Seizure17.12.03.001--
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Shock24.06.02.002--Not Available
Sinus bradycardia02.03.03.0090.002770%
Sleep disorder19.02.04.001--Not Available
Somnambulism19.02.03.006; 17.15.02.0040.001847%Not Available
Somnolence19.02.05.003; 17.02.04.0060.016619%
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.0030.001847%Not Available
Stomatitis07.05.06.005--
Strangury20.02.02.017--Not Available
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