Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triazolam
Drug ID BADD_D02277
Description Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Indications and Usage For the short-term treatment of insomnia.
Marketing Status approved; investigational
ATC Code N05CD05
DrugBank ID DB00897
KEGG ID D00387
MeSH ID D014229
PubChem ID 5556
TTD Drug ID D0U3LS
NDC Product Code 12828-0041; 0009-0017; 50090-6471; 59762-3717; 43353-451; 70710-1521; 71335-1876; 0009-5188; 42816-0017; 67763-128; 0054-4858; 50742-645; 43063-996; 50742-646; 59762-3718; 70710-1289; 70771-1576; 50090-4733; 70771-1162; 0054-4859
UNII 1HM943223R
Synonyms Triazolam | U-33,030 | U 33,030 | U33,030 | Halcion | Trilam | Apo-Triazo | Apo Triazo | Gen-Triazolam | Gen Triazolam
Chemical Information
Molecular Formula C17H12Cl2N4
CAS Registry Number 28911-01-5
SMILES CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscle spasms15.05.03.004--
Muscle spasticity17.05.03.007; 15.05.04.011--
Muscular weakness17.05.03.005; 15.05.06.001--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Neuroleptic malignant syndrome17.05.02.003; 15.05.04.015; 12.03.01.003; 08.05.01.0050.000403%Not Available
Neutrophil count13.01.06.046--Not Available
Nightmare19.02.03.003--Not Available
Non-cardiogenic pulmonary oedema24.03.08.004; 22.01.03.0060.000604%Not Available
Oedema14.05.06.010; 08.01.07.0060.000403%Not Available
Osteoarthritis15.01.04.001--Not Available
Pain08.01.08.004--
Palpitations02.11.04.0120.000403%
Pancreatitis07.18.01.0010.000403%
Paraesthesia23.03.03.094; 17.02.06.005--
Paranoia19.05.01.005--Not Available
Personality disorder19.05.02.002--Not Available
Presyncope02.11.04.013; 24.06.02.010; 17.02.05.0090.000604%
Pruritus23.03.12.001--
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.0020.000403%Not Available
Pulmonary oedema22.01.03.003; 02.05.02.0030.000403%
Red blood cell count13.01.05.020--Not Available
Respiratory arrest22.02.01.0090.000604%Not Available
Respiratory depression22.02.01.010; 17.02.05.0470.000403%Not Available
Restlessness19.11.02.002; 17.02.05.0210.000403%
Rhabdomyolysis15.05.05.0020.000403%
Sedation17.02.04.0050.000403%Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Shock24.06.02.002--Not Available
Sinus bradycardia02.03.03.0090.000604%
The 5th Page    First    Pre   5 6 7    Next   Last    Total 7 Pages