Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triamcinolone acetonide
Drug ID BADD_D02272
Description Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses.[L8249] Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.[L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.[L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients with macular edema associated with uveitis.[L38963]
Indications and Usage For the treatment of perennial and seasonal allergic rhinitis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A01AC01; C05AA12; D07AB09; D07XB02; H02AB08; R01AD11; R03BA06; S01BA05
DrugBank ID DB00620
KEGG ID D00983
MeSH ID D014222
PubChem ID 6436
TTD Drug ID Not Available
NDC Product Code 72189-277; 53002-9121; 0713-0676; 72603-108; 0065-0543; 49999-150; 62011-0320; 76420-162; 44118-711; 63629-8783; 68788-7814; 63187-214; 63629-8782; 70518-3373; 16714-150; 70121-1168; 41250-443; 68788-0149; 70121-1657; 68071-4168; 68071-2339; 41520-443; 63629-8708; 50090-1444; 33342-333; 68462-131; 68071-4397; 0713-0229; 59779-746; 22552-0032; 70121-1655; 70121-1651; 68071-2464; 16714-130; 70121-1652; 50090-2360; 68071-4630; 70518-1094; 67438-045; 0713-0225; 46439-8742; 71205-451; 71205-108; 63629-8778; 33342-331; 70518-0075; 12516-1510; 71565-040; 68071-4286; 52128-173; 0003-0293; 0703-0241; 0168-0003; 0168-0004; 51672-1284; 60432-560; 0703-0243; 68071-1623; 76420-085; 11822-0443; 0003-0494; 0703-0245; 63629-8456; 0168-0005; 49076-6701; 0713-0679; 49035-443; 68071-5070; 52565-011; 45802-045; 71205-124; 71161-135; 41167-5800; 63629-8785; 71205-627; 0316-0175; 71205-009; 66267-934; 35573-404; 70121-1049; 68788-7797; 45802-065; 53002-0150; 76420-220; 50090-4106; 68462-798; 71205-033; 76420-222; 45802-063; 51552-0033; 68071-4564; 24208-040; 21130-443; 12516-1509; 82298-123; 0713-0655; 45802-055; 71205-038; 41167-5900; 64380-871; 67877-317; 16714-140; 72189-039; 37808-443; 50090-2658; 52945-068; 50090-0819; 63187-025; 0003-0315; 50090-0295; 12516-1508; 50090-0162; 63629-8780; 0316-0165; 63629-8779; 0713-0228; 36800-621; 55910-280; 70518-2403; 33342-332; 74157-901; 68071-2516; 72603-202; 68071-2294; 11673-717; 63629-8781; 0363-0811; 60722-3012; 0316-0170; 64380-870; 45802-109; 0168-0002; 33342-328; 67877-251; 66267-933; 68788-7048; 51672-1335; 0168-0006; 70752-130; 0113-0443; 69842-244; 63187-495; 53002-9130; 59088-733; 61919-650; 63629-2407; 70121-1169; 68071-2362; 52565-010; 53002-9330; 63187-661; 45802-049; 67877-318; 46122-385; 76003-1145; 50090-3522; 72603-401; 10631-093; 0113-7005; 30142-443; 52565-056; 76420-203; 52817-811; 63629-8841; 68071-4391; 50090-2542; 68788-7501; 50090-0293; 68788-9172; 46287-010; 53002-0151; 70529-048; 63981-443; 50090-3802; 45802-064; 70121-1654; 33342-329; 45802-817; 50090-0256; 46439-8730; 45802-054; 63629-8707; 53002-9120; 33342-327; 63629-2406; 51927-0134; 64980-320; 70518-2393; 65089-0008; 68071-1803; 51672-1282; 49452-7900; 50090-0362; 52565-014; 0713-0226; 38779-0011; 70121-1653; 68788-7506; 68462-797; 57582-018; 51672-1267; 42571-385; 63187-870; 61919-594; 69256-443; 53002-9333; 59088-843; 50090-3754; 70000-0204; 53002-9334; 62991-1156; 70752-129; 46439-8703; 72288-443; 68071-2361; 70518-2285; 61919-619; 68071-1872; 30142-813; 70518-2938; 24470-922; 68071-4383; 52565-048; 45865-898; 60432-561; 49999-216; 53002-9331; 64980-429; 63275-9943; 70518-2963; 53002-9770; 64380-901; 41163-443; 40032-097; 51862-290; 0713-0766; 68071-4561; 63187-053
Synonyms Triamcinolone Acetonide | Acetonide, Triamcinolone | Cinonide | Tricort-40 | Tricort 40 | Tricort40 | Kenalog | Kenalog 40 | Azmacort | Kenacort A
Chemical Information
Molecular Formula C24H31FO6
CAS Registry Number 76-25-5
SMILES CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin exfoliation23.03.07.003--Not Available
Skin hyperpigmentation23.05.01.003--
Skin hypopigmentation23.05.02.003--
Skin irritation23.03.04.009--Not Available
Skin striae23.01.05.002--Not Available
Small intestinal perforation07.04.06.006--
Sneezing22.02.05.011--
Sodium retention14.05.04.003--Not Available
Spermatozoa progressive motility abnormal13.20.01.003--Not Available
Spinal compression fracture12.04.04.001; 15.08.05.004; 14.04.04.003--Not Available
Steroid withdrawal syndrome08.06.02.013; 19.04.02.014; 05.01.02.007--Not Available
Suicidal ideation19.12.01.003--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Systemic lupus erythematosus10.04.03.004; 23.03.02.006; 15.06.02.003--Not Available
Tachycardia02.03.02.007--Not Available
Telangiectasia24.03.03.003; 23.06.03.001--
Tendon rupture15.07.01.008; 12.01.07.003--Not Available
Tenosynovitis15.07.01.004--Not Available
Teratogenicity12.03.01.032; 03.02.01.004--Not Available
Thrombophlebitis24.01.02.001--Not Available
Tooth disorder07.09.05.001--Not Available
Toothache07.09.06.001--
Tuberculosis11.04.01.006--Not Available
Ulcer08.03.06.001--Not Available
Urinary tract infection11.01.14.004; 20.08.02.001--
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
Vasculitis24.05.02.001; 10.02.02.006--
Vasculitis necrotising10.02.02.008; 24.05.02.002--Not Available
Vertigo17.02.12.002; 04.04.01.003--
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