Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Trandolaprilat
Drug ID BADD_D02260
Description The active metabolite of the prodrug [Trandolapril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14209
KEGG ID Not Available
MeSH ID C061095
PubChem ID 5464097
TTD Drug ID Not Available
NDC Product Code Not Available
UNII RR6866VL0O
Synonyms trandolaprilat | 1-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid | trandolaprilate | RU 44 403 | RU-44403 | RU 44403 | trandolaprilat, (2S-(1R*(R*)),2alpha,3aalpha,7abeta)-isomer | trandolaprilat, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-isomer | trandolaprilat, (2S-(1(S*(R*)),2alpha,3aalpha,7abeta))-isomer
Chemical Information
Molecular Formula C22H30N2O5
CAS Registry Number 87679-71-8
SMILES CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastritis07.08.02.001--
Gastrointestinal pain07.01.05.005--
Gout14.09.01.001; 15.01.06.001--Not Available
Granulocytosis01.02.01.008--Not Available
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkalaemia14.05.03.001--
Hypocalcaemia14.04.01.004--
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
Insomnia19.02.01.002; 17.15.03.002--
Intermittent claudication24.04.03.001--Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Libido decreased19.08.03.001; 21.03.02.005--
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003--
Muscle spasms15.05.03.004--
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nausea07.01.07.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain in extremity15.03.04.010--
Palpitations02.11.04.012--
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