| Drug Name |
Tizanidine |
| Drug ID |
BADD_D02230 |
| Description |
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. It may also be caused by musculoskeletal injury [A177583]. Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition.
Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons promoting muscle spasm [FDA label]. |
| Indications and Usage |
For the management of increased muscle tone associated with spasticity |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
M03BX02 |
| DrugBank ID |
DB00697
|
| KEGG ID |
D08611
|
| MeSH ID |
C023754
|
| PubChem ID |
5487
|
| TTD Drug ID |
D01MDT
|
| NDC Product Code |
50090-0840; 63629-8533; 61919-221; 68084-775; 63187-673; 43063-455; 50090-0813; 63629-7037; 60505-0251; 68788-9497; 67296-1599; 67296-1567; 70771-1335; 63629-3209; 71335-0737; 50090-0841; 16714-172; 55154-7287; 70934-811; 71610-455; 60760-694; 71610-228; 71610-451; 53002-1418; 63187-009; 50090-2078; 71335-1016; 70518-1598; 50090-0811; 57664-502; 71610-167; 71205-311; 60760-719; 71335-1799; 70518-0573; 68788-7782; 63629-1673; 70518-0133; 50090-5767; 68788-7991; 57664-503; 42291-809; 55111-179; 70771-1336; 60505-0252; 70518-1439; 60760-505; 63187-145; 0904-6418; 43353-167; 29300-168; 0615-8360; 68071-3288; 0904-6898; 71335-0424; 63187-493; 68071-5268; 42291-808; 63629-6432; 68788-9514; 72578-096; 68788-7781; 43063-868; 0615-8274; 70934-268; 71610-345; 50090-2208; 71610-162; 68071-4463; 16714-171; 55111-180; 63187-910; 50268-759; 70518-2210; 67296-1192; 35356-662; 29300-169; 68084-645; 70518-3112; 60760-253; 70518-3181; 60760-782; 68788-6365; 67296-1417; 50436-1180; 67877-614; 60760-263; 71335-0003; 72578-097; 63629-2370; 71335-0914; 50268-760; 68788-6444; 67877-613; 63629-2371; 71610-355 |
| Synonyms |
tizanidine | 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole | Zanaflex | tizanidine hydrochloride | tizanidine monohydrochloride | DS 103-282 | Sirdalud |
