| Drug Name |
Terbinafine |
| Drug ID |
BADD_D02160 |
| Description |
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.[A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.[A1279,A1281,L9068]
Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064] |
| Indications and Usage |
For the treatment of dermatophyte infections of the toenail or fingernail caused by susceptible fungi. Also for the treatment of tinea capitis (scalp ringworm) and tinea corporis (body ringworm) or tinea cruris (jock itch). |
| Marketing Status |
OTC; Discontinued; Prescription |
| ATC Code |
D01AE15; D01BA02 |
| DrugBank ID |
DB00857
|
| KEGG ID |
D02375
|
| MeSH ID |
D000077291
|
| PubChem ID |
1549008
|
| TTD Drug ID |
D01AYJ
|
| NDC Product Code |
72189-243; 63187-213; 69097-859; 59349-0008; 70518-1191; 76282-209; 62135-572; 71335-1668; 71205-152 |
| Synonyms |
Terbinafine | Terbinafine, (Z)-isomer | Terbinafine, (Z)- | Lamisil | (E)-N-(6,6-Dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride | TDT-067 | TDT 067 | TDT067 | DA 5505 | SF 86-327 | SF 86 327 | SF 86327 | SF-86-327 | SF86327 | Terbinafine Hydrochloride |
