Drug Name |
Tenecteplase |
Drug ID |
BADD_D02152 |
Description |
Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain. |
Indications and Usage |
For treatment of myocardial infarction and lysis of intracoronary emboli |
Marketing Status |
Prescription |
ATC Code |
B01AD11 |
DrugBank ID |
DB00031
|
KEGG ID |
D06070
|
MeSH ID |
D000077785
|
PubChem ID |
Not Available
|
TTD Drug ID |
D0FX8A
|
NDC Product Code |
50242-120 |
Synonyms |
Tenecteplase | Metalyse | TNKase |